ID

15581

Description

Principal Investigator: Luisa Klotz Collaborator: Novartis Information provided by (Responsible Party):University Hospital Muenster -Study to Assess Immune Function and MRI Disease Activity in RRMS Patients When Switching From Natalizumab to Gilenya (ToFingo2) Purpose A trial in patients with relapsing remitting multiple sclerosis (RRMS) Main objectives: •To evaluate changes in the reconstitution of immune surveillance over time upon switching from natalizumab to fingolimod assessed by a change in the expression of CD49d. •To evaluate changes in the migratory capacity of immune cells/peripheral blood mononuclear cells (PBMCs) upon switching from natalizumab to fingolimod in an in-vitro model of the blood-brain-barrier (BBB). •To evaluate changes in paraclinical disease activity over time upon switching from natalizumab to fingolimod assessed by MRI (changes in Gd+, T2w lesions and DTI). •To evaluate changes in T1w / FLAIR lesions upon switching from natalizumab to fingolimod. For further Information please visit https://clinicaltrials.gov/ct2/show/NCT02325440

Link

https://clinicaltrials.gov/ct2/show/NCT02325440

Keywords

Versions (1)
  1. 6/3/16 6/3/16 -
Uploaded on

June 3, 2016

DOI

To request one please log in.

License

Creative Commons BY 4.0
Model comments :

You can comment on the data model here. Via the speech bubbles at the itemgroups and items you can add comments to those specificially.

Back to model comments
Itemgroup comments for :

Item comments for :

In order to download data models you must be logged in. Please log in or register for free.

ToFingo Screening V1 Study relevant assessments NCT02325440

English

ToFingo Screening V1 Study relevant assessments NCT02325440

1 forms  
Study relevant assessments
Description

Study relevant assessments

Alias
UMLS CUI-1
C3472195
Pregnancy test; Serum
Description

Pregnancy test; Serum

Data type

float

Measurement units
  • U/L
Alias
UMLS CUI [1]
C1880076
U/L
Peripheral blood taken
Description

Peripheral blood taken

Data type

boolean

Alias
UMLS CUI [1]
C0005834
Date of collection
Description

Date of collection

Data type

date

Alias
UMLS CUI [1,1]
C0005834
UMLS CUI [1,2]
C1317250
Back to the top of the page

Similar models

ToFingo Screening V1 Study relevant assessments NCT02325440

1 forms
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Study relevant assessments
C3472195 (UMLS CUI-1)
Pregnancy test; Serum
Item
Pregnancy test; Serum
float
C1880076 (UMLS CUI [1])
Peripheral blood taken
Item
Peripheral blood taken
boolean
C0005834 (UMLS CUI [1])
Date of collection
Item
Date of collection
date
C0005834 (UMLS CUI [1,1])
C1317250 (UMLS CUI [1,2])
Back to the top of the page 

Contact

Please use this form for feedback, questions and suggestions for improvements.

Fields marked with * are required.

Help

Do you need help on how to use the search function? Please watch the corresponding tutorial video for more details and learn how to use the search function most efficiently.

Watch Tutorial