3.1 Charlson Comorbidity Index (CCI)

Co-morbidities
Description

Co-morbidities

Myocardial Infarction (1 Point)
Description

History of medically documented (ECG and enzyme changes) myocardial infarction

Data type

boolean

Alias
UMLS CUI [1]
C0027051
Congestive cardiac failure (1 Point)
Description

Symptomatic (exertional or paroxysmal nocturnal dyspnoea) CHF with response to specific treatment.

Data type

boolean

Alias
UMLS CUI [1]
C0018802
Peripheral vascular disease (1 Pont)
Description

Intermittent claudication, peripheral arterial bypass for insufficiency, gangrene, acute arterial insufficiency, untreated aneurysm (>6 cm)

Data type

boolean

Alias
UMLS CUI [1]
C0085096
Cerebrovascular disease (except hemiplegia) (1 Point)
Description

History of TIA, or CVA with no or minor sequelae

Data type

boolean

Alias
UMLS CUI [1]
C0007820
Dementia (1 Pont)
Description

Chronic cognitive deficit

Data type

boolean

Alias
UMLS CUI [1]
C0497327
Chronic obstructive pulmonary disease (1 Point)
Description

Symptomatic dyspnoea (with moderate activity) due to chronic respiratory conditions (including asthma)

Data type

boolean

Alias
UMLS CUI [1]
C0024117
Connective tissue disease (1 Point)
Description

SLE, polymyositis, mixed CTD, polymyalgia rheumatica, moderate to severe RA.

Data type

boolean

Alias
UMLS CUI [1]
C0009782
Ulcers (1 Point)
Description

Patients who have required treatment for PUD, including those who have bled from ulcers.

Data type

boolean

Alias
UMLS CUI [1]
C0041582
Mild liver disease (1 Point)
Description

Cirrhosis without PHT, chronic hepatitis

Data type

boolean

Alias
UMLS CUI [1]
C0023895
Diabetes mellitus (without end-organ damage) (1 Point)
Description

Diabetes with medication

Data type

boolean

Alias
UMLS CUI [1]
C0011849
Diabetes mellitus (with end-organ damage) (2 Points)
Description

Retinopathy, neuropathy, nephropathy

Data type

boolean

Alias
UMLS CUI [1,1]
C0011849
UMLS CUI [1,2]
C0743496
Hemiplegia (2 Points)
Description

Hemiplegia or paraplegia

Data type

boolean

Alias
UMLS CUI [1]
C0018991
Moderate/Severe chronic renal failure (2 Points)
Description

Creatinine >3 mg/dl (265 mmol/l), dialysis, transplantation, uremic syndrome. According to International Society for Geriatric Oncology serum creatinine alone is insufficient as a means of evaluating renal function, and creatinine clearance should at least be calculated in every patient (Cockcroft-Gault equations) Launay-Vacher V, et al; International Society of Geriatric Oncology. Renal insufficiency in elderly cancer patients: International Society of Geriatric Oncology clinical practice recommendations. Ann Oncol. 2007 Aug;18(8):1314-21.

Data type

boolean

Alias
UMLS CUI [1,1]
C0022661
UMLS CUI [1,2]
C0205081
UMLS CUI [2,1]
C0022661
UMLS CUI [2,2]
C0205082
Second malignancy (non metastatic) (2 Points)
Description

Initially treated in the last 5 years. Exclude non-melanomatous skin cancers and in situ cervical carcinoma.

Data type

boolean

Alias
UMLS CUI [1]
C0085183
Leukaemia (2 Points)
Description

CML, CLL, AML, ALL, PV

Data type

boolean

Alias
UMLS CUI [1]
C0023418
Lymphoma (2 Points)
Description

Non-Hodgkin's lymphoma (NHL), Hodgkin's, Waldenstroem, multiple myeloma

Data type

boolean

Alias
UMLS CUI [1]
C0024299
Moderate / Severe liver disease (3 Points)
Description

Cirrhosis with PHT +/- variceal bleeding

Data type

boolean

Alias
UMLS CUI [1]
C0023895
Second malignancy (metastatic) (6 Points)
Description

Self-explanatory

Data type

boolean

Alias
UMLS CUI [1,1]
C0085183
UMLS CUI [1,2]
C0027627
AIDS (6 Points)
Description

AIDS and AIDS-related complex, Suggested: as defined in latest definition

Data type

boolean

Alias
UMLS CUI [1]
C0001175
Total points (0-37)
Description

Total points

Data type

integer

Alias
UMLS CUI [1,1]
C2964552
UMLS CUI [1,2]
C1516737

Similar models

3.1 Charlson Comorbidity Index (CCI)

Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Co-morbidities
Myocardial infarction
Item
Myocardial Infarction (1 Point)
boolean
C0027051 (UMLS CUI [1])
Congestive cardiac failure
Item
Congestive cardiac failure (1 Point)
boolean
C0018802 (UMLS CUI [1])
Peripheral vascular disease
Item
Peripheral vascular disease (1 Pont)
boolean
C0085096 (UMLS CUI [1])
Cerebrovascular disease
Item
Cerebrovascular disease (except hemiplegia) (1 Point)
boolean
C0007820 (UMLS CUI [1])
Dementia
Item
Dementia (1 Pont)
boolean
C0497327 (UMLS CUI [1])
Chronic obstructive pulmonary disease
Item
Chronic obstructive pulmonary disease (1 Point)
boolean
C0024117 (UMLS CUI [1])
Connective tissue disease
Item
Connective tissue disease (1 Point)
boolean
C0009782 (UMLS CUI [1])
Ulcers
Item
Ulcers (1 Point)
boolean
C0041582 (UMLS CUI [1])
Mild Liver disease
Item
Mild liver disease (1 Point)
boolean
C0023895 (UMLS CUI [1])
Diabetes mellitus (without end-organ damage)
Item
Diabetes mellitus (without end-organ damage) (1 Point)
boolean
C0011849 (UMLS CUI [1])
Diabetes mellitus (with end-organ damage)
Item
Diabetes mellitus (with end-organ damage) (2 Points)
boolean
C0011849 (UMLS CUI [1,1])
C0743496 (UMLS CUI [1,2])
Hemiplegia
Item
Hemiplegia (2 Points)
boolean
C0018991 (UMLS CUI [1])
Chronic renal failure
Item
Moderate/Severe chronic renal failure (2 Points)
boolean
C0022661 (UMLS CUI [1,1])
C0205081 (UMLS CUI [1,2])
C0022661 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
Second malignancy
Item
Second malignancy (non metastatic) (2 Points)
boolean
C0085183 (UMLS CUI [1])
Leukaemia
Item
Leukaemia (2 Points)
boolean
C0023418 (UMLS CUI [1])
Lymphoma
Item
Lymphoma (2 Points)
boolean
C0024299 (UMLS CUI [1])
Liver disease
Item
Moderate / Severe liver disease (3 Points)
boolean
C0023895 (UMLS CUI [1])
Second malignancy
Item
Second malignancy (metastatic) (6 Points)
boolean
C0085183 (UMLS CUI [1,1])
C0027627 (UMLS CUI [1,2])
AIDS
Item
AIDS (6 Points)
boolean
C0001175 (UMLS CUI [1])
Total points
Item
Total points (0-37)
integer
C2964552 (UMLS CUI [1,1])
C1516737 (UMLS CUI [1,2])