Mantle cell lymphoma Subtypes WHO tumor classification
Item
all histologic mcl subtypes (who classification)
boolean
C0334634 (UMLS CUI [1,1])
C0872379 (UMLS CUI [1,2])
C1301142 (UMLS CUI [1,3])
Age
Item
age between 18 and 70 years old
boolean
C0001779 (UMLS CUI [1])
ECOG performance status
Item
performance status 0 to 2 (ecog)
boolean
C1520224 (UMLS CUI [1])
Cardiac ejection fraction
Item
cardiac ejection fraction >50%
boolean
C0232174 (UMLS CUI [1])
Liver function | Cardiac function | Renal function | Bone Marrow function | Hemoglobin measurement | Neutrophil count | Platelet Count measurement | Creatinine measurement, serum | Serum total bilirubin measurement | Aspartate aminotransferase measurement | Alanine aminotransferase measurement
Item
adequate organ (hepatic, cardiac and renal) and marrow function: hb> 10g/dl, neutrophil counts> 1500/ µl, platelet> 100000/ µl. creatinine < 2,5xuln, bilirubin, ast or alt<2,5xuln.
boolean
C0232741 (UMLS CUI [1])
C0232164 (UMLS CUI [2])
C0232804 (UMLS CUI [3])
C0005953 (UMLS CUI [4,1])
C0031843 (UMLS CUI [4,2])
C0518015 (UMLS CUI [5])
C0200633 (UMLS CUI [6])
C0032181 (UMLS CUI [7])
C0201976 (UMLS CUI [8])
C1278039 (UMLS CUI [9])
C0201899 (UMLS CUI [10])
C0201836 (UMLS CUI [11])
yttrium-90-ibritumomab tiuxetan Administration | Bone marrow infiltration Percentage Lymphoma cells | Platelet Count measurement | Neutrophil count
Item
for y90-ibritumomab tiuxetan administration: bone marrow infiltration by lymphoma cells < than 25% ; platelet count >100,000/µl and neutrophil counts >1500/µl
boolean
C1134535 (UMLS CUI [1,1])
C1533734 (UMLS CUI [1,2])
C3854434 (UMLS CUI [2,1])
C0439165 (UMLS CUI [2,2])
C0883208 (UMLS CUI [2,3])
C0032181 (UMLS CUI [3])
C0200633 (UMLS CUI [4])
Informed Consent
Item
informed consent should be obtained
boolean
C0021430 (UMLS CUI [1])
Ann Arbor lymphoma staging system | B-Symptoms Absent | Bulky Disease Tumor size
Item
ann arbor stages i or ii without b symptoms or bulky disease (>10 cm).
boolean
C0432516 (UMLS CUI [1])
C1706867 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C1511341 (UMLS CUI [3,1])
C0475440 (UMLS CUI [3,2])
Chemotherapy | Therapeutic radiology procedure
Item
previous chemotherapy or radiotherapy treatment.
boolean
C0392920 (UMLS CUI [1])
C1522449 (UMLS CUI [2])
Illness Uncontrolled | Liver diseases | Kidney Diseases | Cardiovascular Diseases | nervous system disorder | Metabolic Diseases
Item
uncontrolled current illness: hepatic, renal, cardiovascular, neurological or metabolic illness.
boolean
C0221423 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0023895 (UMLS CUI [2])
C0022658 (UMLS CUI [3])
C0007222 (UMLS CUI [4])
C0027765 (UMLS CUI [5])
C0025517 (UMLS CUI [6])
Symptomatic congestive heart failure | Angina, Unstable | Cardiac Arrhythmia
Item
symptomatic congestive heart failure, unstable angina pectoris, clinically significant cardiac arrhythmia.
boolean
C0742758 (UMLS CUI [1])
C0002965 (UMLS CUI [2])
C0003811 (UMLS CUI [3])
HIV Seropositivity | Hepatitis B Virus Seropositive | Hepatitis C virus Seropositive
Item
hiv, hbv or hcv positive serology.
boolean
C0019699 (UMLS CUI [1])
C0019169 (UMLS CUI [2,1])
C0521143 (UMLS CUI [2,2])
C0220847 (UMLS CUI [3,1])
C0521143 (UMLS CUI [3,2])
Protocol Compliance Limited
Item
limitation of the patient´s ability to comply with the treatment or follow-up protocol.
boolean
C0525058 (UMLS CUI [1,1])
C0439801 (UMLS CUI [1,2])
Females & males of reproductive potential Contraceptive methods Lacking
Item
men and women with reproductive potential who are not using effective contraceptive methods during and at least 12 months after the end of the study
boolean
C4034483 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C0332268 (UMLS CUI [1,3])
Communicable Disease | Chronic infection
Item
acute or chronic active infection.
boolean
C0009450 (UMLS CUI [1])
C0151317 (UMLS CUI [2])
Hypersensitivity Investigational New Drugs | Hypersensitivity Compound Related
Item
known hypersensitivity to some of the drugs or other related compounds
boolean
C0020517 (UMLS CUI [1,1])
C0013230 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C1706082 (UMLS CUI [2,2])
C0439849 (UMLS CUI [2,3])
Informed Consent Missing
Item
no informed consent obtained
boolean
C0021430 (UMLS CUI [1,1])
C1705492 (UMLS CUI [1,2])