non-hodgkin lymphoma, prior therapy
Item
non-hodgkin's lymphoma patients with prior therapy who satisfy the conditions listed below. no restrictions regarding gender.
boolean
C0024305 (UMLS CUI [1,1])
C1514463 (UMLS CUI [1,2])
indolent b cell non-hodgkin lymphoma, mantle cell kymphoma
Item
patients with histologically or cytologically confirmed indolent b cell non-hodgkin's lymphoma or mantle cell lymphoma.
boolean
C1334170 (UMLS CUI [1,1])
C0079731 (UMLS CUI [1,2])
C0024305 (UMLS CUI [1,3])
C0334634 (UMLS CUI [2])
prior therapy, non responder
Item
patients who had not received treatment for at least 4 weeks (for at least 12 weeks in the case of antibody therapy) after completion of prior therapy and who are judged to carry no effect from the prior therapy.
boolean
C1514463 (UMLS CUI [1,1])
C0919875 (UMLS CUI [1,2])
age
Item
patients aged from 20 to less than 75 years.
boolean
C0001779 (UMLS CUI [1])
performance status
Item
performance status (p.s.): 0 or 1.
boolean
C1518965 (UMLS CUI [1])
organ function bone marrow, heart, lung, liver, and kidney
Item
patients with adequately maintained organ functions (e.g., bone marrow, heart, lung, liver, and kidney functions).
boolean
C0678852 (UMLS CUI [1,1])
C0005953 (UMLS CUI [1,2])
C0232164 (UMLS CUI [2])
C0231921 (UMLS CUI [3])
C0232741 (UMLS CUI [4])
C0232804 (UMLS CUI [5])
informed consent
Item
patients from whom written consent to participate in this study has been obtained.
boolean
C0021430 (UMLS CUI [1])
exclusion criteria
Item
patients who meet any of the following criteria will be excluded.
boolean
C0680251 (UMLS CUI [1])
infection
Item
patients with apparent infections.
boolean
C3714514 (UMLS CUI [1])
hepatic failure or renal failure
Item
patients with serious complications (hepatic failure or renal failure).
boolean
C0085605 (UMLS CUI [1])
C0035078 (UMLS CUI [2])
heart failure, cardiac infarction, ischemic heart disease
Item
patients with complication or history of serious heart failure (e.g. cardiac infarction, ischemic heart disease).
boolean
C0018801 (UMLS CUI [1,1])
C0027051 (UMLS CUI [1,2])
C0151744 (UMLS CUI [1,3])
serious digestive symptoms (nausea/ vomiting/ diarrhea)
Item
patients with serious digestive symptoms (nausea/ vomiting/ diarrhea).
boolean
C0205404 (UMLS CUI [1,1])
C0476288 (UMLS CUI [1,2])
C0027497 (UMLS CUI [1,3])
C0042963 (UMLS CUI [1,4])
C0011991 (UMLS CUI [1,5])
hbv, hcv, hiv
Item
patients who are known to be positive for hbv, hcv or hiv.
boolean
C0019163 (UMLS CUI [1,1])
C0019196 (UMLS CUI [1,2])
C0019682 (UMLS CUI [1,3])
other investigational drugs
Item
patients receiving other investigational drugs within 3 months before registration in the study.
boolean
C0013230 (UMLS CUI [1])
allogenic bone-marrow transplant
Item
patients with allogenic bone-marrow transplant.
boolean
C0149615 (UMLS CUI [1])
pregnancy, childbearing potential, breast feeding
Item
women who are pregnant, of childbearing potential, or lactating.
boolean
C0032961 (UMLS CUI [1])
C3831118 (UMLS CUI [2])
C0006147 (UMLS CUI [3])
contraceptive methods
Item
patients who do not agree to contraception.
boolean
C0700589 (UMLS CUI [1])
unsuitable
Item
otherwise, patients who are judged by the investigator as being unsuitable for inclusion in the study.
boolean
C3844399 (UMLS CUI [1])