WHO tumor classification
Item
1. patients must have a diagnosis of one of the following histologic types according to the who classification:
boolean
C1301142 (UMLS CUI [1])
Angioimmunoblastic Lymphadenopathy
Item
angioimmunoblastic t-cell lymphoma
boolean
C0020981 (UMLS CUI [1])
Nasal Type Extranodal NK/T-Cell Lymphoma
Item
extranodal nk/t-cell lymphoma, nasal type
boolean
C0392788 (UMLS CUI [1])
Enteropathy-Associated T-Cell Lymphoma
Item
enteropathy-type t-cell lymphoma
boolean
C0456889 (UMLS CUI [1])
Hepatosplenic T-cell lymphoma
Item
hepatosplenic gamma-delta t-cell lymphoma
boolean
C1333984 (UMLS CUI [1])
Subcutaneous panniculitis-like T-cell lymphoma
Item
subcutaneous panniculitis-like t-cell lymphoma
boolean
C0522624 (UMLS CUI [1])
Anaplastic large cell lymphoma, T/Null cell, primary systemic type
Item
anaplastic large-cell lymphoma, t/null cell, primary systemic type
boolean
C1531540 (UMLS CUI [1])
Peripheral T-Cell Lymphoma
Item
peripheral t-cell lymphoma, not otherwise characterized
boolean
C0079774 (UMLS CUI [1])
Biopsy sample Hematologist review
Item
all biopsy specimens including patients whose diagnosis have been made outside king chulalongkorn memorial hospital will be reviewed by an expert hematopathologist at department of pathology, king chulalongkorn memorial hospital.
boolean
C0677862 (UMLS CUI [1,1])
C2923847 (UMLS CUI [1,2])
Newly Diagnosed | Age
Item
2. newly diagnosed, age 15 - 65 years.
boolean
C1518321 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Work up Complete | Evaluation | Measurement
Item
3. complete work up for baseline evaluation and measurement (appendix b).
boolean
C0750430 (UMLS CUI [1,1])
C0205197 (UMLS CUI [1,2])
C1261322 (UMLS CUI [2])
C0242485 (UMLS CUI [3])
Informed Consent
Item
4. patient's free written inform consent.
boolean
C0021430 (UMLS CUI [1])
Hypersensitivity murine protein | Hypersensitivity Alemtuzumab Component
Item
1. patients with a known hypersensitivity to murine proteins or to any component of alemtuzumab.
boolean
C0020517 (UMLS CUI [1,1])
C1699668 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0383429 (UMLS CUI [2,2])
C1705248 (UMLS CUI [2,3])
Chemotherapy Lymphoma | Therapeutic radiology procedure Lymphoma
Item
2. patients who have received prior antilymphoma treatment with chemotherapy or radiotherapy.
boolean
C0392920 (UMLS CUI [1,1])
C0024299 (UMLS CUI [1,2])
C1522449 (UMLS CUI [2,1])
C0024299 (UMLS CUI [2,2])
poor performance status ECOG performance status
Item
3. patients with poor performance status (ps; ecog criteria of 3-4)(appendix c).
boolean
C1831741 (UMLS CUI [1,1])
C1520224 (UMLS CUI [1,2])
HIV Exposure Evidence Serologic
Item
4. serologic evidence of human immunodeficiency virus exposure.
boolean
C0019682 (UMLS CUI [1,1])
C0332157 (UMLS CUI [1,2])
C3887511 (UMLS CUI [1,3])
C0205473 (UMLS CUI [1,4])
Cardiac Status Impaired | Myocardial Infarction
Item
5. patients with history of impaired cardiac status or myocardial infarction.
boolean
C1999091 (UMLS CUI [1,1])
C0221099 (UMLS CUI [1,2])
C0027051 (UMLS CUI [2])
Creatinine measurement, serum | Elevated total bilirubin | Aspartate aminotransferase increased | Alanine aminotransferase increased | Serum creatinine level Due to Involvement with Malignant Neoplasm | Elevated total bilirubin Due to Involvement with Malignant Neoplasm | Aspartate aminotransferase increased Due to Involvement with Malignant Neoplasm | Alanine aminotransferase increased Due to Involvement with Malignant Neoplasm
Item
6. patients with serum creatinine > 1.8 mg/dl, bilirubin > 1.5 times upper limit of normal range, sgot or sgpt > 3 times upper limit of normal range, unless due to tumor involvement.
boolean
C0201976 (UMLS CUI [1])
C0741494 (UMLS CUI [2])
C0151904 (UMLS CUI [3])
C0151905 (UMLS CUI [4])
C0600061 (UMLS CUI [5,1])
C0678226 (UMLS CUI [5,2])
C1314939 (UMLS CUI [5,3])
C0006826 (UMLS CUI [5,4])
C0741494 (UMLS CUI [6,1])
C0678226 (UMLS CUI [6,2])
C1314939 (UMLS CUI [6,3])
C0006826 (UMLS CUI [6,4])
C0151904 (UMLS CUI [7,1])
C0678226 (UMLS CUI [7,2])
C1314939 (UMLS CUI [7,3])
C0006826 (UMLS CUI [7,4])
C0151905 (UMLS CUI [8,1])
C0678226 (UMLS CUI [8,2])
C1314939 (UMLS CUI [8,3])
C0006826 (UMLS CUI [8,4])
Communicable Disease Uncontrolled | Gastric ulcer | Duodenal Ulcer | Diabetic - poor control | Medical condition Severe Exclude Cytotoxic Chemotherapy
Item
7. patients with active uncontrolled infection, active non-malignant gastric or duodenal ulcer, uncontrolled diabetes mellitus or other severe medical conditions which would preclude aggressive cytotoxic chemotherapy.
boolean
C0009450 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0038358 (UMLS CUI [2])
C0013295 (UMLS CUI [3])
C0421258 (UMLS CUI [4])
C3843040 (UMLS CUI [5,1])
C0205082 (UMLS CUI [5,2])
C0332196 (UMLS CUI [5,3])
C0677881 (UMLS CUI [5,4])
Pregnancy | Breast Feeding
Item
8. pregnant or lactating women.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Illness Serious Preventing Informed Consent | Mental disorder Serious Preventing Informed Consent
Item
9. serious medical or psychiatric illness which prevent informed consent.
boolean
C0221423 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C1292733 (UMLS CUI [1,3])
C0021430 (UMLS CUI [1,4])
C0004936 (UMLS CUI [2,1])
C0205404 (UMLS CUI [2,2])
C1292733 (UMLS CUI [2,3])
C0021430 (UMLS CUI [2,4])
Clinical Study Follow-up Patient Availability Unlikely
Item
10. patients who are likely to lost to follow up (e.g., unwilling or difficult to return, cannot be contacted).
boolean
C3274571 (UMLS CUI [1,1])
C0030705 (UMLS CUI [1,2])
C0470187 (UMLS CUI [1,3])
C0750558 (UMLS CUI [1,4])