Eligibility Chronic Myeloid Leukemia NCT02011945

Criteria
Description

Criteria

Inclusion Criteria
Description

Inclusion Criteria

Alias
UMLS CUI
C1512693
confirmed diagnosis of chronic myeloid leukemia in chronic phase or accelerated phase
Description

Leukemia, Myeloid, Chronic-Phase | Leukemia, Myeloid, Accelerated Phase

Data type

boolean

Alias
UMLS CUI [1]
C0023474
UMLS CUI [2]
C0023472
with historically documented ph+ cells
Description

Cells Philadelphia chromosome positive

Data type

boolean

Alias
UMLS CUI [1,1]
C0007634
UMLS CUI [1,2]
C0856536
≥2 prior tyrosine kinase inhibitors (tki) therapies for cml
Description

Protein tyrosine kinase inhibitor therapy Quantity CML

Data type

boolean

Alias
UMLS CUI [1,1]
C0879484
UMLS CUI [1,2]
C1265611
UMLS CUI [1,3]
C0023473
currently progressing, resistance to or with a suboptimal response to their most recent therapy
Description

Disease Progression | Resistant to Therapy | Response Suboptimal Therapy

Data type

boolean

Alias
UMLS CUI [1]
C0242656
UMLS CUI [2,1]
C0332325
UMLS CUI [2,2]
C0087111
UMLS CUI [3,1]
C1704632
UMLS CUI [3,2]
C2984009
UMLS CUI [3,3]
C0087111
eastern cooperative oncology group (ecog) performance status (ps) score 0 - 1
Description

ECOG performance status

Data type

boolean

Alias
UMLS CUI [1]
C1520224
Exclusion Criteria
Description

Exclusion Criteria

Alias
UMLS CUI
C0680251
blast phase cml
Description

Blast Phase CML

Data type

boolean

Alias
UMLS CUI [1]
C0005699
known abl-kinase mutation resistant to dasatinib (e.g. t315i or t315a)
Description

BCR-ABL Mutation Resistant to Dasatinib | T315I mutation | Other Coding

Data type

boolean

Alias
UMLS CUI [1,1]
C0004891
UMLS CUI [1,2]
C0026882
UMLS CUI [1,3]
C0332325
UMLS CUI [1,4]
C1455147
UMLS CUI [2]
C3889036
UMLS CUI [3]
C3846158

Similar models

Eligibility Chronic Myeloid Leukemia NCT02011945

Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Item Group
C1512693 (UMLS CUI)
Leukemia, Myeloid, Chronic-Phase | Leukemia, Myeloid, Accelerated Phase
Item
confirmed diagnosis of chronic myeloid leukemia in chronic phase or accelerated phase
boolean
C0023474 (UMLS CUI [1])
C0023472 (UMLS CUI [2])
Cells Philadelphia chromosome positive
Item
with historically documented ph+ cells
boolean
C0007634 (UMLS CUI [1,1])
C0856536 (UMLS CUI [1,2])
Protein tyrosine kinase inhibitor therapy Quantity CML
Item
≥2 prior tyrosine kinase inhibitors (tki) therapies for cml
boolean
C0879484 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C0023473 (UMLS CUI [1,3])
Disease Progression | Resistant to Therapy | Response Suboptimal Therapy
Item
currently progressing, resistance to or with a suboptimal response to their most recent therapy
boolean
C0242656 (UMLS CUI [1])
C0332325 (UMLS CUI [2,1])
C0087111 (UMLS CUI [2,2])
C1704632 (UMLS CUI [3,1])
C2984009 (UMLS CUI [3,2])
C0087111 (UMLS CUI [3,3])
ECOG performance status
Item
eastern cooperative oncology group (ecog) performance status (ps) score 0 - 1
boolean
C1520224 (UMLS CUI [1])
Item Group
C0680251 (UMLS CUI)
Blast Phase CML
Item
blast phase cml
boolean
C0005699 (UMLS CUI [1])
BCR-ABL Mutation Resistant to Dasatinib | T315I mutation | Other Coding
Item
known abl-kinase mutation resistant to dasatinib (e.g. t315i or t315a)
boolean
C0004891 (UMLS CUI [1,1])
C0026882 (UMLS CUI [1,2])
C0332325 (UMLS CUI [1,3])
C1455147 (UMLS CUI [1,4])
C3889036 (UMLS CUI [2])
C3846158 (UMLS CUI [3])