Arthritis, Psoriatic | Classification Criteria Psoriatic Arthritis | Tender joint count | Swollen joint count | Exception Interphalangeal joints Distal
Item
subject has a diagnosis of psoriatic arthritis (by the classification of psoriatic arthritis criteria (caspar), with ≥ 3 tender and ≥ 3 swollen joints (excluding the distal interphalangeal joints)).
boolean
C0003872 (UMLS CUI [1])
C0008902 (UMLS CUI [2,1])
C0243161 (UMLS CUI [2,2])
C0003872 (UMLS CUI [2,3])
C0451530 (UMLS CUI [3])
C0451521 (UMLS CUI [4])
C1705847 (UMLS CUI [5,1])
C1563055 (UMLS CUI [5,2])
C0205108 (UMLS CUI [5,3])
Psoriasis Skin lesion Quantity | Erosion Quantity Radiography | Elevated C-reactive protein
Item
subjects must have at least 1 psoriatic skin lesion as well as either ≥ 1 erosion on a centrally read radiograph or an elevated crp.
boolean
C0033860 (UMLS CUI [1,1])
C0037284 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C3887524 (UMLS CUI [2,1])
C1265611 (UMLS CUI [2,2])
C0034571 (UMLS CUI [2,3])
C0742906 (UMLS CUI [3])
Tuberculosis
Item
subject has known history of active tuberculosis.
boolean
C0041296 (UMLS CUI [1])
Surgical intervention Planned
Item
subject has a planned surgical intervention between baseline and the week 52 evaluation.
boolean
C0549433 (UMLS CUI [1,1])
C1301732 (UMLS CUI [1,2])
Communicable Diseases
Item
subject has an active infection or history of infections.
boolean
C0009450 (UMLS CUI [1])
Systemic disease Uncontrolled | Kidney Failure | Heart failure | Hypertensive disease | Liver disease | Diabetes Mellitus | Anemia
Item
subject has any systemic disease (eg, renal failure, heart failure, hypertension, liver disease, diabetes, anemia) considered by the investigator to be clinically significant and uncontrolled.
boolean
C0442893 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0035078 (UMLS CUI [2])
C0018801 (UMLS CUI [3])
C0020538 (UMLS CUI [4])
C0023895 (UMLS CUI [5])
C0011849 (UMLS CUI [6])
C0002871 (UMLS CUI [7])
Comorbidity At risk Study Subject | Electrocardiogram abnormal At risk Study Subject
Item
subject has any concurrent medical condition or electrocardiogram (ecg) abnormality that, in the opinion of the investigator, could cause this study to be detrimental to the subject.
boolean
C0009488 (UMLS CUI [1,1])
C1444641 (UMLS CUI [1,2])
C0681850 (UMLS CUI [1,3])
C0522055 (UMLS CUI [2,1])
C1444641 (UMLS CUI [2,2])
C0681850 (UMLS CUI [2,3])
Severe depression Patient Health Questionnaire - 9 Item | Feeling suicidal Columbia suicide severity rating scale | Suicidal behavior Columbia suicide severity rating scale
Item
subject has severe depression measured by personal health questionnaire depression scale (phq-8) or suicidal ideation/behavior as measured by and columbia suicide severity rating scale (e-cssrs)
boolean
C0588008 (UMLS CUI [1,1])
C4083201 (UMLS CUI [1,2])
C0424000 (UMLS CUI [2,1])
C3888485 (UMLS CUI [2,2])
C1760428 (UMLS CUI [3,1])
C3888485 (UMLS CUI [3,2])
Mental disorders At risk Patient safety | Substance Use Disorders At risk Patient safety
Item
subject has a history or evidence of psychiatric disorder or substance abuse considered by the investigator to pose a risk to subject safety
boolean
C0004936 (UMLS CUI [1,1])
C1444641 (UMLS CUI [1,2])
C1113679 (UMLS CUI [1,3])
C0038586 (UMLS CUI [2,1])
C1444641 (UMLS CUI [2,2])
C1113679 (UMLS CUI [2,3])