age 18 Years to 65 Years
Item
age 18 Years to 65 Years
boolean
C0001779 (UMLS CUI 2011AA)
397669002 (SNOMED CT 2011_0131)
Disease: Cytologically proven primary or therapy-related myelodysplastic syndrome (MDS), either as
Item
Disease: Cytologically proven primary or therapy-related myelodysplastic syndrome (MDS), either as
boolean
C0012634 (UMLS CUI 2011AA)
64572001 (SNOMED CT 2011_0131)
C0205471 (UMLS CUI 2011AA)
40413002 (SNOMED CT 2011_0131)
C0456369 (UMLS CUI 2011AA)
277025001 (SNOMED CT 2011_0131)
CL414904 (UMLS CUI 2011AA)
C0026986 (UMLS CUI 2011AA)
128623006 (SNOMED CT 2011_0131)
10028533 (MedDRA 14.1)
D46 (ICD-10-CM Version 2010)
238.75 (ICD-9-CM Version 2011)
E12552 (CTCAE 1105E)
C0011900 (UMLS CUI 2011AA)
439401001 (SNOMED CT 2011_0131)
MTHU008876 (LOINC Version 232)
C1292780 (UMLS CUI 2011AA)
128838005 (SNOMED CT 2011_0131)
refractory anaemia (RA) according FAB or RA with or without dysplasia according WHO,
Item
refractory anaemia (RA) according FAB or RA with or without dysplasia according WHO,
boolean
C0002893 (UMLS CUI 2011AA)
109996008 (SNOMED CT 2011_0131)
10038269 (MedDRA 14.1)
C0332290 (UMLS CUI 2011AA)
385433004 (SNOMED CT 2011_0131)
CL421536 (UMLS CUI 2011AA)
C0451584 (UMLS CUI 2011AA)
273931002 (SNOMED CT 2011_0131)
C0150312 (UMLS CUI 2011AA)
52101004 (SNOMED CT 2011_0131)
C0332197 (UMLS CUI 2011AA)
2667000 (SNOMED CT 2011_0131)
C0334044 (UMLS CUI 2011AA)
25723000 (SNOMED CT 2011_0131)
10058314 (MedDRA 14.1)
refractory anaemia with ringsideroblasts (RARS) according FAB or RARS with or without dysplasia according WHO,
Item
refractory anaemia with ringsideroblasts (RARS) according FAB or RARS with or without dysplasia according WHO,
boolean
C1264195 (UMLS CUI 2011AA)
109998009 (SNOMED CT 2011_0131)
10038272 (MedDRA 14.1)
D46.1 (ICD-10-CM Version 2010)
C0332290 (UMLS CUI 2011AA)
385433004 (SNOMED CT 2011_0131)
CL421536 (UMLS CUI 2011AA)
C0451584 (UMLS CUI 2011AA)
273931002 (SNOMED CT 2011_0131)
C0150312 (UMLS CUI 2011AA)
52101004 (SNOMED CT 2011_0131)
C0332197 (UMLS CUI 2011AA)
2667000 (SNOMED CT 2011_0131)
C0334044 (UMLS CUI 2011AA)
25723000 (SNOMED CT 2011_0131)
10058314 (MedDRA 14.1)
refractory anaemia with excess of blasts (RAEB) according FAB or RAEB I or RAEB II according WHO,
Item
refractory anaemia with excess of blasts (RAEB) according FAB or RAEB I or RAEB II according WHO,
boolean
C0002894 (UMLS CUI 2011AA)
398623004 (SNOMED CT 2011_0131)
10038270 (MedDRA 14.1)
D46.20 (ICD-10-CM Version 2010)
C0332290 (UMLS CUI 2011AA)
385433004 (SNOMED CT 2011_0131)
CL421536 (UMLS CUI 2011AA)
C0451584 (UMLS CUI 2011AA)
273931002 (SNOMED CT 2011_0131)
C1318550 (UMLS CUI 2011AA)
415283002 (SNOMED CT 2011_0131)
D46.21 (ICD-10-CM Version 2010)
C1318551 (UMLS CUI 2011AA)
415284008 (SNOMED CT 2011_0131)
D46.22 (ICD-10-CM Version 2010)
refractory anaemia with excess of blast in transformation (RAEB T) according FAB,
Item
refractory anaemia with excess of blast in transformation (RAEB T) according FAB,
boolean
C0280028 (UMLS CUI 2011AA)
110000005 (SNOMED CT 2011_0131)
10054593 (MedDRA 14.1)
C92.0 (ICD-10-CM Version 2010)
C0332290 (UMLS CUI 2011AA)
385433004 (SNOMED CT 2011_0131)
CL421536 (UMLS CUI 2011AA)
CMML (dysplastic type) according WHO,
Item
CMML (dysplastic type) according WHO,
boolean
C0023480 (UMLS CUI 2011AA)
127225006 (SNOMED CT 2011_0131)
10009018 (MedDRA 14.1)
C93.1 (ICD-10-CM Version 2010)
C0334044 (UMLS CUI 2011AA)
25723000 (SNOMED CT 2011_0131)
10058314 (MedDRA 14.1)
C0332307 (UMLS CUI 2011AA)
410657003 (SNOMED CT 2011_0131)
MTHU013727 (LOINC Version 232)
C0332290 (UMLS CUI 2011AA)
385433004 (SNOMED CT 2011_0131)
C0451584 (UMLS CUI 2011AA)
273931002 (SNOMED CT 2011_0131)
or secondary acute myeloid leukaemia (sAML).
Item
Secondary Acute Myeloid Leukemia
boolean
C0280449 (UMLS CUI 2011AA)
Blast count < 20 percent in bone marrow with or without chemotherapy at time of transplantation.
Item
Blast count < 20 percent in bone marrow with or without chemotherapy at time of transplantation.
boolean
C0523113 (UMLS CUI 2011AA)
104102000 (SNOMED CT 2011_0131)
10061700 (MedDRA 14.1)
C0005953 (UMLS CUI 2011AA)
14016003 (SNOMED CT 2011_0131)
MTHU016536 (LOINC Version 232)
C0150312 (UMLS CUI 2011AA)
52101004 (SNOMED CT 2011_0131)
C0332197 (UMLS CUI 2011AA)
2667000 (SNOMED CT 2011_0131)
C0392920 (UMLS CUI 2011AA)
150415003 (SNOMED CT 2011_0131)
C0439547 (UMLS CUI 2011AA)
272105005 (SNOMED CT 2011_0131)
C0040732 (UMLS CUI 2011AA)
77465005 (SNOMED CT 2011_0131)
10057677 (MedDRA 14.1)
Patient eligible for standard and dose-reduced conditioning as per local guideline.
Item
Patient eligible for standard and dose-reduced conditioning as per local guideline.
boolean
C1548635 (UMLS CUI 2011AA)
ELG (HL7 V3 2006_05)
C2828392 (UMLS CUI 2011AA)
C1707814 (UMLS CUI 2011AA)
C0009647 (UMLS CUI 2011AA)
78326006 (SNOMED CT 2011_0131)
C0220845 (UMLS CUI 2011AA)
Patient age 18 - 60 years if donor is a HLA-matched unrelated donor (HLA-A, HLA-B, HLA-DRB1 and HLA-DQB1) (one mismatch allowed):
Item
Patient age 18 - 60 years if donor is a HLA-matched unrelated donor (HLA-A, HLA-B, HLA-DRB1 and HLA-DQB1) (one mismatch allowed):
boolean
C0001779 (UMLS CUI 2011AA)
397669002 (SNOMED CT 2011_0131)
C0750557 (UMLS CUI 2011AA)
C3179133 (UMLS CUI 2011AA)
C0019728 (UMLS CUI 2011AA)
49495002 (SNOMED CT 2011_0131)
MTHU033943 (LOINC Version 232)
C0019737 (UMLS CUI 2011AA)
54481006 (SNOMED CT 2011_0131)
MTHU027937 (LOINC Version 232)
C0122040 (UMLS CUI 2011AA)
MTHU019559 (LOINC Version 232)
C0122020 (UMLS CUI 2011AA)
MTHU019561 (LOINC Version 232)
Patient age 18 - 65 years if donor is a HLA-matched related donor ((HLA-A, HLA-B, HLA-DRB1 and HLA-DQB1) (one antigen-mismatch allowed):
Item
Patient age 18 - 65 years if donor is a HLA-matched related donor ((HLA-A, HLA-B, HLA-DRB1 and HLA-DQB1) (one antigen-mismatch allowed):
boolean
C0001779 (UMLS CUI 2011AA)
397669002 (SNOMED CT 2011_0131)
C0750557 (UMLS CUI 2011AA)
C0445223 (UMLS CUI 2011AA)
262094002 (SNOMED CT 2011_0131)
CL414920 (UMLS CUI 2011AA)
C0019728 (UMLS CUI 2011AA)
49495002 (SNOMED CT 2011_0131)
MTHU033943 (LOINC Version 232)
C0019737 (UMLS CUI 2011AA)
54481006 (SNOMED CT 2011_0131)
MTHU027937 (LOINC Version 232)
C0122040 (UMLS CUI 2011AA)
MTHU019559 (LOINC Version 232)
C0122020 (UMLS CUI 2011AA)
MTHU019561 (LOINC Version 232)
No major organ dysfunction.
Item
No major organ dysfunction.
boolean
C0332197 (UMLS CUI 2011AA)
2667000 (SNOMED CT 2011_0131)
C0205164 (UMLS CUI 2011AA)
255603008 (SNOMED CT 2011_0131)
C0178784 (UMLS CUI 2011AA)
MTHU020170 (LOINC Version 232)
C0277785 (UMLS CUI 2011AA)
386585008 (SNOMED CT 2011_0131)
Written informed consent of the patient.
Item
Written informed consent of the patient.
boolean
C1576874 (UMLS CUI 2011AA)
WRITTEN (HL7 V3 2006_05)
C0021430 (UMLS CUI 2011AA)
Blasts > 20 % in bone marrow at time of transplantation
Item
Blasts > 20 % in bone marrow at time of transplantation
boolean
C0005953 (UMLS CUI 2011AA)
14016003 (SNOMED CT 2011_0131)
MTHU016536 (LOINC Version 232)
C1262102 (UMLS CUI 2011AA)
10062274 (MedDRA 14.1)
C0439547 (UMLS CUI 2011AA)
272105005 (SNOMED CT 2011_0131)
C0040732 (UMLS CUI 2011AA)
77465005 (SNOMED CT 2011_0131)
10057677 (MedDRA 14.1)
No written informed consent.
Item
No written informed consent.
boolean
C1705492 (UMLS CUI 2011AA)
C1576874 (UMLS CUI 2011AA)
WRITTEN (HL7 V3 2006_05)
C0021430 (UMLS CUI 2011AA)
Central nervous involvement.
Item
Central nervous system (CNS) involvement status
boolean
C0449389 (UMLS CUI 2011AA)
260766009 (SNOMED CT 2011_0131)
Severe irreversible renal, hepatic, pulmonary or cardiac disease, such as
Item
Severe irreversible renal, hepatic, pulmonary or cardiac disease, such as
boolean
C0205082 (UMLS CUI 2011AA)
24484000 (SNOMED CT 2011_0131)
C0860433 (UMLS CUI 2011AA)
10022997 (MedDRA 14.1)
C0023895 (UMLS CUI 2011AA)
235856003 (SNOMED CT 2011_0131)
10024670 (MedDRA 14.1)
K76.9 (ICD-10-CM Version 2010)
573.9 (ICD-9-CM Version 2011)
C0024115 (UMLS CUI 2011AA)
19829001 (SNOMED CT 2011_0131)
10025082 (MedDRA 14.1)
J98.4 (ICD-10-CM Version 2010)
C0018799 (UMLS CUI 2011AA)
56265001 (SNOMED CT 2011_0131)
10061024 (MedDRA 14.1)
Total bilirubin, SGPT or SGOT > 2 times upper the normal level.
Item
Total bilirubin, SGPT or SGOT > 2 times upper the normal level.
boolean
C0201913 (UMLS CUI 2011AA)
359986008 (SNOMED CT 2011_0131)
10004696 (MedDRA 14.1)
C0001899 (UMLS CUI 2011AA)
56935002 (SNOMED CT 2011_0131)
MTHU006766 (LOINC Version 232)
C0004002 (UMLS CUI 2011AA)
26091008 (SNOMED CT 2011_0131)
MTHU004883 (LOINC Version 232)
C1519815 (UMLS CUI 2011AA)
Left ventricular ejection fraction < 30 %.
Item
LVEF - Left ventricular ejection fraction
boolean
C0428772 (UMLS CUI 2011AA)
250908004 (SNOMED CT 2011_0131)
10069170 (MedDRA 14.1)
Creatinine clearance < 30 ml/min.
Item
Creatinine clearance (CrCl) measurement
boolean
C0373595 (UMLS CUI 2011AA)
167181009 (SNOMED CT 2011_0131)
10011371 (MedDRA 14.1)
DLCO < 35 % and/or receiving supplementary continuous oxygen.
Item
DLCO < 35 % and/or receiving supplementary continuous oxygen.
boolean
C1516251 (UMLS CUI 2011AA)
C1514756 (UMLS CUI 2011AA)
C0750536 (UMLS CUI 2011AA)
C0919655 (UMLS CUI 2011AA)
10050322 (MedDRA 14.1)
Positive serology for HIV.
Item
HIV Seropositivity
boolean
C0019699 (UMLS CUI 2011AA)
165816005 (SNOMED CT 2011_0131)
10020188 (MedDRA 14.1)
Z21 (ICD-10-CM Version 2010)
Pregnant or lactating women.
Item
Pregnant or lactating women.
boolean
C0549206 (UMLS CUI 2011AA)
10036586 (MedDRA 14.1)
C2828358 (UMLS CUI 2011AA)
C0043210 (UMLS CUI 2011AA)
224526002 (SNOMED CT 2011_0131)
Patients with a life-expectancy of < six months because of another debilitating disease.
Item
Patients with a life-expectancy of < six months because of another debilitating disease.
boolean
C0023671 (UMLS CUI 2011AA)
LP75025-4 (LOINC Version 232)
C0439092 (UMLS CUI 2011AA)
276139006 (SNOMED CT 2011_0131)
LT (HL7 V3 2006_05)
C0205452 (UMLS CUI 2011AA)
68244004 (SNOMED CT 2011_0131)
C0439231 (UMLS CUI 2011AA)
258706009 (SNOMED CT 2011_0131)
MO (HL7 V3 2006_05)
C0205394 (UMLS CUI 2011AA)
74964007 (SNOMED CT 2011_0131)
C1883552 (UMLS CUI 2011AA)
260407003 (SNOMED CT 2011_0131)
10011942 (MedDRA 14.1)
R53.1 (ICD-10-CM Version 2010)
C0012634 (UMLS CUI 2011AA)
64572001 (SNOMED CT 2011_0131)
Serious psychiatric or psychological disorders.
Item
Serious psychiatric or psychological disorders.
boolean
C0205404 (UMLS CUI 2011AA)
42745003 (SNOMED CT 2011_0131)
C0004936 (UMLS CUI 2011AA)
74732009 (SNOMED CT 2011_0131)
10037174 (MedDRA 14.1)
F99 (ICD-10-CM Version 2010)
290-319.99 (ICD-9-CM Version 2011)
Invasive fungal infection at time of registration.
Item
Invasive fungal infection at time of registration.
boolean
C0205281 (UMLS CUI 2011AA)
10179008 (SNOMED CT 2011_0131)
C0026946 (UMLS CUI 2011AA)
3218000 (SNOMED CT 2011_0131)
10017533 (MedDRA 14.1)
B35-B49 (ICD-10-CM Version 2010)
110-118.99 (ICD-9-CM Version 2011)