T-Cell Lymphoma untreated | NK-cell lymphoma | Lymphoma CD30 positive ALK positive
Item
1. confirmed diagnosis of previously untreated t-cell non hodgkin's lymphomas and nk lymphomas, with the exception of cluster of differentiation antigen 30 (cd30+) alk1+
boolean
C0079772 (UMLS CUI [1,1])
C0332155 (UMLS CUI [1,2])
C3647364 (UMLS CUI [2])
C0024299 (UMLS CUI [3,1])
C3888910 (UMLS CUI [3,2])
C0252409 (UMLS CUI [3,3])
C1514241 (UMLS CUI [3,4])
Adult Anaplastic Large Cell Lymphoma T-cell | Skin Involvement | Systemic disease Skin Involvement | Therapeutic procedure Topical
Item
t-anaplastic large cell lymphoma (alcl). patients with skin involvement alone are also excluded. for patients with skin involvement as part of systemic disease, prior topical treatment only is allowed.
boolean
C1332182 (UMLS CUI [1,1])
C0039194 (UMLS CUI [1,2])
C1123023 (UMLS CUI [2,1])
C1314939 (UMLS CUI [2,2])
C0442893 (UMLS CUI [3,1])
C1123023 (UMLS CUI [3,2])
C1314939 (UMLS CUI [3,3])
C0087111 (UMLS CUI [4,1])
C1522168 (UMLS CUI [4,2])
Zubrod Performance Status
Item
2. patients with a performance status of 3 or less (zubrod scale - see appendix d).
boolean
C3714786 (UMLS CUI [1])
Serum total bilirubin measurement | Creatinine measurement, serum | Absolute neutrophil count | Platelet Count measurement
Item
3. serum bilirubin </= 1.5 mg/dl and serum creatinine </= 2.0 mg/dl unless due to lymphoma; absolute neutrophil count (anc) >/= 1000 mm^3 and platelets >/= 100,000 mm^3 unless due to lymphoma.
boolean
C1278039 (UMLS CUI [1])
C0201976 (UMLS CUI [2])
C0948762 (UMLS CUI [3])
C0032181 (UMLS CUI [4])
Cardiac ejection fraction | MUGA | Echocardiography
Item
4. cardiac ejection fraction 50% or greater by multigated radionuclide angiography (muga) or echocardiogram.
boolean
C0232174 (UMLS CUI [1])
C0521317 (UMLS CUI [2])
C0013516 (UMLS CUI [3])
Age
Item
5. ages 18 and older.
boolean
C0001779 (UMLS CUI [1])
Transfusion, blood or blood components
Item
6. patients must be willing to receive transfusions of blood products.
boolean
C0371802 (UMLS CUI [1])
T-Anaplastic Large Cell Lymphoma CD30 positive ALK Positive | Skin Involvement
Item
1. patients with cd30+ alk1+ t-anaplastic large cell lymphoma (alcl) or patients with skin involvement alone.
boolean
C1332182 (UMLS CUI [1,1])
C0039194 (UMLS CUI [1,2])
C3888910 (UMLS CUI [1,3])
C0252409 (UMLS CUI [1,4])
C1514241 (UMLS CUI [1,5])
C1123023 (UMLS CUI [2,1])
C1314939 (UMLS CUI [2,2])
Pregnancy
Item
2. pregnancy
boolean
C0032961 (UMLS CUI [1])
HIV Seropositivity
Item
3. hiv positive serology
boolean
C0019699 (UMLS CUI [1])
Central Nervous System Involvement
Item
4. central nervous system (cns) involvement
boolean
C4050309 (UMLS CUI [1])
Comorbidity Excludes Chemotherapy High dose | Liver Cirrhosis | Child-Pugh Classification | Kidney Failure, Chronic | Symptomatic congestive heart failure | Mental disorders
Item
5. co-morbid medical, such as child's class c liver cirrhosis, end-stage renal disease, and symptomatic congestive heart failure, or psychiatric illnesses that preclude treatment with intense dose chemotherapy as determined by the primary investigator
boolean
C0009488 (UMLS CUI [1,1])
C0332196 (UMLS CUI [1,2])
C3665472 (UMLS CUI [1,3])
C0444956 (UMLS CUI [1,4])
C0023890 (UMLS CUI [2])
C4050412 (UMLS CUI [3])
C0022661 (UMLS CUI [4])
C0742758 (UMLS CUI [5])
C0004936 (UMLS CUI [6])
Malignant Neoplasm Prognosis bad | Continuance of life Percentage Probability
Item
6. concurrent or previous malignancy whose prognosis is poor (<90% probability of survival at 5 years)
boolean
C0006826 (UMLS CUI [1,1])
C0278252 (UMLS CUI [1,2])
C0038952 (UMLS CUI [2,1])
C0439165 (UMLS CUI [2,2])
C0033204 (UMLS CUI [2,3])