ID

37537

Beschrijving

ICHOM Cleft Lip and Palate Study description: ICHOM Cleft Lip and Palate data collection Version 3.0.6 Revised: March 20th, 2017 International Consortium for Health Outcomes Measurement (ICHOM), Source: http://www.ichom.org/ For Cleft Lip and Palate, the following conditions and treatment approaches (or interventions) are covered by our Standard Set. Conditions: Cleft Lip | Cleft Palate | Cleft Lip and Alveolus | Cleft Lip and Palate | Robin Sequence | 22q11 | CL&P Associated with Other Craniofacial Abnormalities | CL&P Associated with Other Congenital Abnormalities Treatment approaches: Audiology | Otology | Speech/Communication | Feeding/Nutrition | Plastic Surgery | Oral & Maxillofacial Surgery | Dentistry | Orthodontics | Pediatrics | Nursing | Genetics | Social Work | Psychology/Psychiatry This document contains the Baseline - Clinical Form. It has to be filled in at index event (first doctor’s visit). Collecting Patient-Reported Outcome Measure: CLEFT-Q. As there is no permission for publication of this questionnaire on this portal, only the total score will be included in this version of the standard set. Nasal Obstruction NOSE Scale-Patient . The study for development and validation of the NOSE Scale was funded by the AAO-HNS/F. If others wish to use the tool, there is no cost, but the study should be referenced: Stewart MG, Witsell DL, Smith TL, Weaver EM, Yueh B, Hannley MT. Development and validation of the Nasal Obstruction Symptom Evaluation (NOSE) scale. Otolaryngol Head Neck Surg 2004;130:157-63. COHIP Oral Symptoms Scale-Patient. The COHIP is free for all health care organizations, and a license is not needed according to ICHOM. Broder HL, McGrath C, Cisneros GJ. Questionnaire development: Face validity and item impact testing of the child oral health impact profile Community Dent Oral Epidemiol 2007; 35 Suppl 1:8-19. Intelligibility in Context Scale (ICS)-Parent. The ICS is free for all health care organizations, and a license is not needed (according to ICHOM). McLeod, S., Harrison, L. J., & McCormack, J. (2012). Intelligibility in Context Scale. Bathurst, NSW, Australia: Charles Sturt University. Available at http://www.csu.edu.au/research/multilingual-speech/ics under CC 3.0 by-nc-nd. PCC-Clinician. The PCC is free for all health care organizations, and a license is not needed. Reference: Allori, A. C., Kelley, T., Meara, J. G., Albert, A., Bonanthaya, K., Chapman, K., … Wong, K. W. (2017). A Standard Set of Outcome Measures for the Comprehensive Appraisal of Cleft Care. The Cleft Palate-Craniofacial Journal, 54(5), 540–554 The Standard set of ICHOM was supported by the Boston Children’s Hospital, The Children’s Hospital of Philadelphia. Texas Children’s Hospital and the Great Ormond Street Hospital.

Link

http://www.ichom.org/

Trefwoorden

  1. 06-08-19 06-08-19 -
  2. 12-08-19 12-08-19 -
  3. 30-04-20 30-04-20 - Sarah Riepenhausen
  4. 20-09-21 20-09-21 -
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ICHOM

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6 augustus 2019

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ICHOM Cleft Lip and Palate

Baseline - Clinical Form

Administrative Data
Beschrijving

Administrative Data

Alias
UMLS CUI-1
C1320722
Indicate the patient's medical record number
Beschrijving

This number will not be shared with ICHOM. In the case patient-level data is submitted to ICHOM for benchmarking or research purposes, a separate ICHOM Patient Identifier will be created and cross-linking between the ICHOM Patient Identifier and the medical record number will only be known at the treating institution INCLUSION CRITERIA: All patients TIMING: On all forms REPORTING SOURCE: Administrative or clinical RESPONSE OPTIONS: According to institution

Datatype

integer

Alias
UMLS CUI [1]
C1269815
Demographic factors
Beschrijving

Demographic factors

Alias
UMLS CUI-1
C1704791
Indicate the patient’s sex at birth
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline REPORTING SOURCE: Clinical, parent-reported, or patient-reported TYPE: Single answer

Datatype

integer

Alias
UMLS CUI [1]
C0079399
What is the patient's/your ethnicity?
Beschrijving

In the original form response option is N/A. A codelist ist not included because it varies by country and should be determined by country (not for cross-country comparison). INCLUSION CRITERIA: All patients TIMING: Baseline REPORTING SOURCE: Clinical, parent-reported, or patient-reported TYPE: Single answer

Datatype

text

Alias
UMLS CUI [1]
C0034510
Baseline Clinical Status
Beschrijving

Baseline Clinical Status

Alias
UMLS CUI-1
C0449440
UMLS CUI-2
C1442488
Indicate the patient’s category
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline REPORTING SOURCE: Clinical TYPE: Single answer

Datatype

integer

Alias
UMLS CUI [1,1]
C0031437
UMLS CUI [1,2]
C0683312
Indicate the patient’s severity of lip
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline REPORTING SOURCE: Clinical TYPE: Single answer

Datatype

integer

Alias
UMLS CUI [1,1]
C0008924
UMLS CUI [1,2]
C0439793
UMLS CUI [1,3]
C0205092
Indicate the patient’s severity of lip
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline REPORTING SOURCE: Clinical TYPE: Single answer

Datatype

integer

Alias
UMLS CUI [1,1]
C0008924
UMLS CUI [1,2]
C0439793
UMLS CUI [1,3]
C0238767
Specification of asymmetric lip
Beschrijving

Note: This item does not exist in the original standard set. If you tick "Asymmetric" in the item "PHENSEVBI", you can fill in this item additionally for specification. INCLUSION CRITERIA: All patients TIMING: Baseline REPORTING SOURCE: Clinical TYPE: Free text

Datatype

text

Alias
UMLS CUI [1,1]
C0008924
UMLS CUI [1,2]
C0439793
UMLS CUI [1,3]
C0238767
UMLS CUI [2,1]
C2348235
UMLS CUI [2,2]
C0332514
Indicate the patient’s severity of alveolus
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline REPORTING SOURCE: Clinical TYPE: Single answer

Datatype

integer

Alias
UMLS CUI [1,1]
C1534709
UMLS CUI [1,2]
C0447411
UMLS CUI [1,3]
C0439793
UMLS CUI [1,4]
C0227130
Indicate the patient’s classification of palate
Beschrijving

SUPPORTING DEFINITION: Veau I: Cleft of soft palate only Veau II: Midline cleft of secondary hard and soft palate Veau III: Unilateral cleft of hard and soft palate, including alveolus Veau IV: Bilateral cleft of hard and soft palate, including both alveoli INCLUSION CRITERIA: All patients TIMING: Baseline REPORTING SOURCE: Clinical TYPE: Single answer

Datatype

integer

Alias
UMLS CUI [1,1]
C0700374
UMLS CUI [1,2]
C0008925
UMLS CUI [1,3]
C0008902
Indicate if the patient has a genetically confirmed mutation that is known to be associated with cleft lip and palate
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline REPORTING SOURCE: Clinical TYPE: Single answer

Datatype

integer

Alias
UMLS CUI [1,1]
C0008925
UMLS CUI [1,2]
C0596612
UMLS CUI [2,1]
C4321245
UMLS CUI [2,2]
C0596612
Indicate which mutation
Beschrijving

INCLUSION CRITERIA: All patients If answered 'yes' that the patient has a genetically confirmed mutation that is known to be associated with cleft lip and palate (GENETICSYN) TIMING: Baseline REPORTING SOURCE: Clinical TYPE: Single answer

Datatype

integer

Alias
UMLS CUI [1,1]
C0008925
UMLS CUI [1,2]
C0026882
UMLS CUI [2,1]
C4321245
UMLS CUI [2,2]
C0026882
Indicate if the patient has any of the following comorbidities 0 = No other diseases
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline and ongoing REPORTING SOURCE: Clinical TYPE: Multiple answer, Separate multiple entries with "";""

Datatype

boolean

Alias
UMLS CUI [1]
C0009488
UMLS CUI [2,1]
C1298908
UMLS CUI [2,2]
C2359476
Indicate if the patient has any of the following comorbidities 1 = Cardiac anomalies or dysfunction
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline and ongoing REPORTING SOURCE: Clinical TYPE: Multiple answer, Separate multiple entries with "";""

Datatype

boolean

Alias
UMLS CUI [1]
C0009488
UMLS CUI [2]
C3277906
UMLS CUI [3]
C0741916
Indicate if the patient has any of the following comorbidities 2 = GU anomalies or dysfunction
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline and ongoing REPORTING SOURCE: Clinical TYPE: Multiple answer, Separate multiple entries with "";""

Datatype

boolean

Alias
UMLS CUI [1]
C0009488
UMLS CUI [2,1]
C0042066
UMLS CUI [2,2]
C1704258
UMLS CUI [3,1]
C0042066
UMLS CUI [3,2]
C3887504
Indicate if the patient has any of the following comorbidities 3 = Developmental delay or learning difficulty
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline and ongoing REPORTING SOURCE: Clinical TYPE: Multiple answer, Separate multiple entries with "";""

Datatype

boolean

Alias
UMLS CUI [1]
C0009488
UMLS CUI [2]
C0424605
UMLS CUI [3]
C0851265
Indicate if the patient has any of the following comorbidities 4 = Psychiatric or behavior disorder
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline and ongoing REPORTING SOURCE: Clinical TYPE: Multiple answer, Separate multiple entries with "";""

Datatype

boolean

Alias
UMLS CUI [1]
C0009488
UMLS CUI [2]
C0004936
UMLS CUI [3]
C0004930
Indicate if the patient has any of the following comorbidities 5 = Infection or toxin mediated disease
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline and ongoing REPORTING SOURCE: Clinical TYPE: Multiple answer, Separate multiple entries with "";""

Datatype

boolean

Alias
UMLS CUI [1]
C0009488
UMLS CUI [2]
C0009450
UMLS CUI [3,1]
C0040549
UMLS CUI [3,2]
C0012634
Indicate if the patient has any of the following comorbidities 6 = GI anomalies or dysfunction
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline and ongoing REPORTING SOURCE: Clinical TYPE: Multiple answer, Separate multiple entries with "";""

Datatype

boolean

Alias
UMLS CUI [1]
C0009488
UMLS CUI [2,1]
C0521362
UMLS CUI [2,2]
C1704258
UMLS CUI [3,1]
C0521362
UMLS CUI [3,2]
C3887504
Indicate if the patient has any of the following comorbidities 7 = Musculoskeletal anomalies or dysfunction
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline and ongoing REPORTING SOURCE: Clinical TYPE: Multiple answer, Separate multiple entries with "";""

Datatype

boolean

Alias
UMLS CUI [1]
C0009488
UMLS CUI [2,1]
C0026860
UMLS CUI [2,2]
C3887504
UMLS CUI [3,1]
C0026860
UMLS CUI [3,2]
C1704258
Indicate if the patient has any of the following comorbidities 8 = Other craniomaxillofacial anomalies
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline and ongoing REPORTING SOURCE: Clinical TYPE: Multiple answer, Separate multiple entries with "";""

Datatype

boolean

Alias
UMLS CUI [1]
C0009488
UMLS CUI [2,1]
C0205394
UMLS CUI [2,2]
C0037303
UMLS CUI [2,3]
C0024947
UMLS CUI [2,4]
C1704258
Indicate if the patient has any of the following comorbidities 9 = Pulmonary anomalies or dysfunction
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline and ongoing REPORTING SOURCE: Clinical TYPE: Multiple answer, Separate multiple entries with "";""

Datatype

boolean

Alias
UMLS CUI [1]
C0009488
UMLS CUI [2,1]
C2709248
UMLS CUI [2,2]
C1704258
UMLS CUI [3]
C1709770
Indicate if the patient has any of the following comorbidities 10 = Hematological anomalies or dysfunction
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline and ongoing REPORTING SOURCE: Clinical TYPE: Multiple answer, Separate multiple entries with "";""

Datatype

boolean

Alias
UMLS CUI [1]
C0009488
UMLS CUI [2,1]
C0279810
UMLS CUI [2,2]
C1704258
UMLS CUI [3,1]
C0279810
UMLS CUI [3,2]
C3887504
Indicate if the patient has any of the following comorbidities 11 = Immunological anomalies or dysfunction
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline and ongoing REPORTING SOURCE: Clinical TYPE: Multiple answer, Separate multiple entries with "";""

Datatype

boolean

Alias
UMLS CUI [1]
C0009488
UMLS CUI [2,1]
C0205470
UMLS CUI [2,2]
C1704258
UMLS CUI [3,1]
C0205470
UMLS CUI [3,2]
C3887504
Indicate if the patient has any of the following comorbidities 12 = Neurological anomalies or dysfunction
Beschrijving

INCLUSION CRITERIA: All patients TIMING: Baseline and ongoing REPORTING SOURCE: Clinical TYPE: Multiple answer, Separate multiple entries with "";""

Datatype

boolean

Alias
UMLS CUI [1]
C0009488
UMLS CUI [2,1]
C0027853
UMLS CUI [2,2]
C1704258
UMLS CUI [3,1]
C0027853
UMLS CUI [3,2]
C3887504

Similar models

Baseline - Clinical Form

Name
Type
Description | Question | Decode (Coded Value)
Datatype
Alias
Item Group
Administrative Data
C1320722 (UMLS CUI-1)
Patient ID
Item
Indicate the patient's medical record number
integer
C1269815 (UMLS CUI [1])
Item Group
Demographic factors
C1704791 (UMLS CUI-1)
Item
Indicate the patient’s sex at birth
integer
C0079399 (UMLS CUI [1])
Code List
Indicate the patient’s sex at birth
CL Item
Male (1)
C1706180 (UMLS CUI-1)
(Comment:en)
CL Item
Female (2)
C0086287 (UMLS CUI-1)
(Comment:en)
CL Item
Undisclosed (999)
C0439673 (UMLS CUI-1)
(Comment:en)
Race/ethnicity
Item
What is the patient's/your ethnicity?
text
C0034510 (UMLS CUI [1])
Item Group
Baseline Clinical Status
C0449440 (UMLS CUI-1)
C1442488 (UMLS CUI-2)
Item
Indicate the patient’s category
integer
C0031437 (UMLS CUI [1,1])
C0683312 (UMLS CUI [1,2])
Code List
Indicate the patient’s category
CL Item
Cleft lip (1)
C0008924 (UMLS CUI-1)
(Comment:en)
CL Item
Cleft palate (2)
C0008925 (UMLS CUI-1)
(Comment:en)
CL Item
Cleft lip and alveolus  (3)
C1298692 (UMLS CUI-1)
(Comment:en)
CL Item
Cleft lip and palate (4)
C0158646 (UMLS CUI-1)
(Comment:en)
Item
Indicate the patient’s severity of lip
integer
C0008924 (UMLS CUI [1,1])
C0439793 (UMLS CUI [1,2])
C0205092 (UMLS CUI [1,3])
Code List
Indicate the patient’s severity of lip
CL Item
Complete (1)
C0205197 (UMLS CUI-1)
(Comment:en)
CL Item
Incomplete  (2)
C0205257 (UMLS CUI-1)
(Comment:en)
CL Item
Lesser-form (3)
C0547044 (UMLS CUI-1)
C0023759 (UMLS CUI-2)
(Comment:en)
Item
Indicate the patient’s severity of lip
integer
C0008924 (UMLS CUI [1,1])
C0439793 (UMLS CUI [1,2])
C0238767 (UMLS CUI [1,3])
Code List
Indicate the patient’s severity of lip
CL Item
Complete (1)
C0205197 (UMLS CUI-1)
(Comment:en)
CL Item
Incomplete (2)
C0205257 (UMLS CUI-1)
(Comment:en)
CL Item
Lesser-form (3)
C0547044 (UMLS CUI-1)
C0023759 (UMLS CUI-2)
(Comment:en)
CL Item
Asymmetric (specify severity of each side) (4)
C0332514 (UMLS CUI-1)
(Comment:en)
Specification of asymmetric lip
Item
Specification of asymmetric lip
text
C0008924 (UMLS CUI [1,1])
C0439793 (UMLS CUI [1,2])
C0238767 (UMLS CUI [1,3])
C2348235 (UMLS CUI [2,1])
C0332514 (UMLS CUI [2,2])
Item
Indicate the patient’s severity of alveolus
integer
C1534709 (UMLS CUI [1,1])
C0447411 (UMLS CUI [1,2])
C0439793 (UMLS CUI [1,3])
C0227130 (UMLS CUI [1,4])
Code List
Indicate the patient’s severity of alveolus
CL Item
Complete (1)
C0205197 (UMLS CUI-1)
(Comment:en)
CL Item
Incomplete  (2)
C0205257 (UMLS CUI-1)
(Comment:en)
CL Item
Notched (3)
C0205316 (UMLS CUI-1)
(Comment:en)
Item
Indicate the patient’s classification of palate
integer
C0700374 (UMLS CUI [1,1])
C0008925 (UMLS CUI [1,2])
C0008902 (UMLS CUI [1,3])
Code List
Indicate the patient’s classification of palate
CL Item
Veau I (1)
C0700374 (UMLS CUI-1)
C0008925 (UMLS CUI-2)
C0008902 (UMLS CUI-3)
C0205447 (UMLS CUI-4)
(Comment:en)
CL Item
Veau II (2)
C0700374 (UMLS CUI-1)
C0008925 (UMLS CUI-2)
C0008902 (UMLS CUI-3)
C0205448 (UMLS CUI-4)
(Comment:en)
CL Item
Veau III (3)
C0700374 (UMLS CUI-1)
C0008925 (UMLS CUI-2)
C0008902 (UMLS CUI-3)
C0205449 (UMLS CUI-4)
(Comment:en)
CL Item
Veau IV (4)
C0700374 (UMLS CUI-1)
C0008925 (UMLS CUI-2)
C0008902 (UMLS CUI-3)
C0205450 (UMLS CUI-4)
(Comment:en)
Item
Indicate if the patient has a genetically confirmed mutation that is known to be associated with cleft lip and palate
integer
C0008925 (UMLS CUI [1,1])
C0596612 (UMLS CUI [1,2])
C4321245 (UMLS CUI [2,1])
C0596612 (UMLS CUI [2,2])
Code List
Indicate if the patient has a genetically confirmed mutation that is known to be associated with cleft lip and palate
CL Item
No  (0)
C1298908 (UMLS CUI-1)
(Comment:en)
CL Item
Yes (1)
C1705108 (UMLS CUI-1)
(Comment:en)
Item
Indicate which mutation
integer
C0008925 (UMLS CUI [1,1])
C0026882 (UMLS CUI [1,2])
C4321245 (UMLS CUI [2,1])
C0026882 (UMLS CUI [2,2])
Code List
Indicate which mutation
CL Item
22q11 (1)
C0935660 (UMLS CUI-1)
(Comment:en)
CL Item
Robin Sequence (2)
C4313661 (UMLS CUI-1)
(Comment:en)
CL Item
Stickler Syndrome  (3)
C0265253 (UMLS CUI-1)
(Comment:en)
CL Item
Treacher Collins (4)
C1855433 (UMLS CUI-1)
(Comment:en)
CL Item
Van der Woude (5)
C0175697 (UMLS CUI-1)
(Comment:en)
CL Item
Other (888)
C0205394 (UMLS CUI-1)
(Comment:en)
Comorbidities: No other diseases
Item
Indicate if the patient has any of the following comorbidities 0 = No other diseases
boolean
C0009488 (UMLS CUI [1])
C1298908 (UMLS CUI [2,1])
C2359476 (UMLS CUI [2,2])
Comorbidities: Cardiac anomalies or dysfunction
Item
Indicate if the patient has any of the following comorbidities 1 = Cardiac anomalies or dysfunction
boolean
C0009488 (UMLS CUI [1])
C3277906 (UMLS CUI [2])
C0741916 (UMLS CUI [3])
Comorbidities: GU anomalies or dysfunction
Item
Indicate if the patient has any of the following comorbidities 2 = GU anomalies or dysfunction
boolean
C0009488 (UMLS CUI [1])
C0042066 (UMLS CUI [2,1])
C1704258 (UMLS CUI [2,2])
C0042066 (UMLS CUI [3,1])
C3887504 (UMLS CUI [3,2])
Comorbidities: Developmental delay or learning difficulty
Item
Indicate if the patient has any of the following comorbidities 3 = Developmental delay or learning difficulty
boolean
C0009488 (UMLS CUI [1])
C0424605 (UMLS CUI [2])
C0851265 (UMLS CUI [3])
Comorbidities: Psychiatric or behavior disorder
Item
Indicate if the patient has any of the following comorbidities 4 = Psychiatric or behavior disorder
boolean
C0009488 (UMLS CUI [1])
C0004936 (UMLS CUI [2])
C0004930 (UMLS CUI [3])
Comorbidities: Infection or toxin mediated disease
Item
Indicate if the patient has any of the following comorbidities 5 = Infection or toxin mediated disease
boolean
C0009488 (UMLS CUI [1])
C0009450 (UMLS CUI [2])
C0040549 (UMLS CUI [3,1])
C0012634 (UMLS CUI [3,2])
Comorbidities: GI anomalies or dysfunction
Item
Indicate if the patient has any of the following comorbidities 6 = GI anomalies or dysfunction
boolean
C0009488 (UMLS CUI [1])
C0521362 (UMLS CUI [2,1])
C1704258 (UMLS CUI [2,2])
C0521362 (UMLS CUI [3,1])
C3887504 (UMLS CUI [3,2])
Comorbidities: Musculoskeletal anomalies or dysfunction
Item
Indicate if the patient has any of the following comorbidities 7 = Musculoskeletal anomalies or dysfunction
boolean
C0009488 (UMLS CUI [1])
C0026860 (UMLS CUI [2,1])
C3887504 (UMLS CUI [2,2])
C0026860 (UMLS CUI [3,1])
C1704258 (UMLS CUI [3,2])
Comorbidities: Other craniomaxillofacial anomalies
Item
Indicate if the patient has any of the following comorbidities 8 = Other craniomaxillofacial anomalies
boolean
C0009488 (UMLS CUI [1])
C0205394 (UMLS CUI [2,1])
C0037303 (UMLS CUI [2,2])
C0024947 (UMLS CUI [2,3])
C1704258 (UMLS CUI [2,4])
Comorbidities: Pulmonary anomalies or dysfunction
Item
Indicate if the patient has any of the following comorbidities 9 = Pulmonary anomalies or dysfunction
boolean
C0009488 (UMLS CUI [1])
C2709248 (UMLS CUI [2,1])
C1704258 (UMLS CUI [2,2])
C1709770 (UMLS CUI [3])
Comorbidities: Hematological anomalies or dysfunction
Item
Indicate if the patient has any of the following comorbidities 10 = Hematological anomalies or dysfunction
boolean
C0009488 (UMLS CUI [1])
C0279810 (UMLS CUI [2,1])
C1704258 (UMLS CUI [2,2])
C0279810 (UMLS CUI [3,1])
C3887504 (UMLS CUI [3,2])
Comorbidities: Immunological anomalies or dysfunction
Item
Indicate if the patient has any of the following comorbidities 11 = Immunological anomalies or dysfunction
boolean
C0009488 (UMLS CUI [1])
C0205470 (UMLS CUI [2,1])
C1704258 (UMLS CUI [2,2])
C0205470 (UMLS CUI [3,1])
C3887504 (UMLS CUI [3,2])
Comorbidities: Neurological anomalies or dysfunction
Item
Indicate if the patient has any of the following comorbidities 12 = Neurological anomalies or dysfunction
boolean
C0009488 (UMLS CUI [1])
C0027853 (UMLS CUI [2,1])
C1704258 (UMLS CUI [2,2])
C0027853 (UMLS CUI [3,1])
C3887504 (UMLS CUI [3,2])

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