Description:

A Phase III Trial of ZD4054 (Zibotentan) (Endothelin A Antagonist) in Non-metastatic Hormone Resistant Prostate Cancer (ENTHUSE M0) see http://clinicaltrials.gov/ct2/show/study/NCT00626548

Lien:
http://clinicaltrials.gov/ct2/show/study/NCT00626548
Mots-clés:
  1. 22/11/2011 22/11/2011 -
  2. 22/11/2011 22/11/2011 -
  3. 27/03/2014 27/03/2014 - Martin Dugas
  4. 13/04/2014 13/04/2014 - Julian Varghese
  5. 17/09/2021 17/09/2021 -
Téléchargé le:

17 septembre 2021

DOI:
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Licence :
Creative Commons BY 4.0
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Eligibility DRKS00003883 NCT00626548 Prostate Cancer

Eligibility NCT00626548

  1. StudyEvent: Eligibility
    1. Eligibility NCT00626548
Inclusion criteria
18 Years and older
Male
Confirmed diagnosis of prostate cancer (adenocarcinoma of the prostate) that has NOT spread to the other parts of the body (metastases). Patients with lymph node involvement may be eligible if specified criteria is met.
Increasing Prostate Specific Antigen (PSA), collected within one year of enrollment
Currently receiving treatment with surgical or medical castration
Exclusion criteria
Currently using opiate based pain killers for cancer related pain
Previous treatment with chemotherapy (paclitaxel, docetaxel, and mitoxantrone). Prior targeted cancer therapies are permitted if received during a previous clinical trial
Suffering from heart failure or had a myocardial infarction within last 6 months
A history of epilepsy or seizures

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