ID

43404

Descrizione

ODM derived from http://clinicaltrials.gov/show/NCT00682396

collegamento

http://clinicaltrials.gov/show/NCT00682396

Keywords

versioni (3)
  1. 09/12/13 09/12/13 - Martin Dugas
  2. 15/04/14 15/04/14 - Julian Varghese
  3. 20/09/21 20/09/21 -
Caricato su

20 settembre 2021

DOI

Per favore, per richiedere un accesso.

Licenza

Creative Commons BY 4.0
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Eligibility NCT00682396 Myelodysplastic Syndrome

Tedesco Inglese

Eligibility

1 moduli  
  1. StudyEvent: Eligibility
    1. Eligibility
Einschlusskriterien
Descrizione

Einschlusskriterien

Alias
UMLS CUI 2011AA
CL425202
Alter 18 bis 65 Jahre
Descrizione

age 18 Years to 65 Years

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0001779
SNOMED CT 2011_0131
397669002
Disease: cytologically proven
Descrizione

Disease: cytologically proven

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0012634
SNOMED CT 2011_0131
64572001
UMLS CUI 2011AA
C0205471
SNOMED CT 2011_0131
40413002
UMLS CUI 2011AA
C0456369
SNOMED CT 2011_0131
277025001
primary or therapy related myelodysplastic syndrome (MDS) either as
Descrizione

primary or therapy related myelodysplastic syndrome (MDS) either as

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
CL414904
UMLS CUI 2011AA
C3463824
SNOMED CT 2011_0131
128623006
MedDRA 14.1
10028533
ICD-10-CM Version 2010
D46
ICD-9-CM Version 2011
238.75
CTCAE 1105E
E12552
UMLS CUI 2011AA
C0011900
SNOMED CT 2011_0131
439401001
LOINC Version 232
MTHU008876
UMLS CUI 2011AA
C1292780
SNOMED CT 2011_0131
128838005
refractory anaemia (RA) according FAB or RA with or without dysplasia according WHO
Descrizione

refractory anaemia (RA) according FAB or RA with or without dysplasia according WHO

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0002893
SNOMED CT 2011_0131
109996008
MedDRA 14.1
10038269
UMLS CUI 2011AA
C0680240
UMLS CUI 2011AA
CL421536
UMLS CUI 2011AA
C0002893
SNOMED CT 2011_0131
109996008
MedDRA 14.1
10038269
UMLS CUI 2011AA
C0150312
SNOMED CT 2011_0131
52101004
UMLS CUI 2011AA
C0332197
SNOMED CT 2011_0131
2667000
UMLS CUI 2011AA
C0334044
SNOMED CT 2011_0131
25723000
MedDRA 14.1
10058314
UMLS CUI 2011AA
C0680240
UMLS CUI 2011AA
C0451584
SNOMED CT 2011_0131
273931002
refractory anaemia with ringsideroblasts (RARS) according FAB or RARS with or without dysplasia according WHO
Descrizione

refractory anaemia with ringsideroblasts (RARS) according FAB or RARS with or without dysplasia according WHO

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C1264195
SNOMED CT 2011_0131
109998009
MedDRA 14.1
10038272
ICD-10-CM Version 2010
D46.1
UMLS CUI 2011AA
C0680240
UMLS CUI 2011AA
CL421536
UMLS CUI 2011AA
C1264195
SNOMED CT 2011_0131
109998009
MedDRA 14.1
10038272
ICD-10-CM Version 2010
D46.1
UMLS CUI 2011AA
C0150312
SNOMED CT 2011_0131
52101004
UMLS CUI 2011AA
C0332197
SNOMED CT 2011_0131
2667000
UMLS CUI 2011AA
C0334044
SNOMED CT 2011_0131
25723000
MedDRA 14.1
10058314
UMLS CUI 2011AA
C0680240
UMLS CUI 2011AA
C0451584
SNOMED CT 2011_0131
273931002
refractory anaemia with excess of blasts (RAEB) according FAB or RAEB I or RAEB II according WHO
Descrizione

refractory anaemia with excess of blasts (RAEB) according FAB or RAEB I or RAEB II according WHO

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0002894
SNOMED CT 2011_0131
398623004
MedDRA 14.1
10038270
ICD-10-CM Version 2010
D46.20
UMLS CUI 2011AA
C0680240
UMLS CUI 2011AA
CL421536
UMLS CUI 2011AA
C1318550
SNOMED CT 2011_0131
415283002
ICD-10-CM Version 2010
D46.21
UMLS CUI 2011AA
C1318551
SNOMED CT 2011_0131
415284008
ICD-10-CM Version 2010
D46.22
UMLS CUI 2011AA
C0680240
UMLS CUI 2011AA
C0451584
SNOMED CT 2011_0131
273931002
refractory anaemia with excess of blast in transformation (RAEB-T) according FAB
Descrizione

refractory anaemia with excess of blast in transformation (RAEB-T) according FAB

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0280028
SNOMED CT 2011_0131
110000005
MedDRA 14.1
10054593
ICD-10-CM Version 2010
C92.0
UMLS CUI 2011AA
C0680240
UMLS CUI 2011AA
CL421536
CMML (dysplastic type) according WHO
Descrizione

CMML (dysplastic type) according WHO

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0023480
SNOMED CT 2011_0131
127225006
MedDRA 14.1
10009018
ICD-10-CM Version 2010
C93.1
UMLS CUI 2011AA
C0334044
SNOMED CT 2011_0131
25723000
MedDRA 14.1
10058314
UMLS CUI 2011AA
C0680240
UMLS CUI 2011AA
C0451584
SNOMED CT 2011_0131
273931002
sekundäre akute myeloische Leukämie
Descrizione

or secondary acute myeloid leukaemia (sAML)

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0280449
Blast count <20 percent in bone marrow with or without chemotherapy at time of transplantation
Descrizione

Blast count <20 percent in bone marrow with or without chemotherapy at time of transplantation

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0523113
SNOMED CT 2011_0131
104102000
MedDRA 14.1
10061700
UMLS CUI 2011AA
C0005953
SNOMED CT 2011_0131
14016003
LOINC Version 232
MTHU016536
UMLS CUI 2011AA
C0150312
SNOMED CT 2011_0131
52101004
UMLS CUI 2011AA
C0332197
SNOMED CT 2011_0131
2667000
UMLS CUI 2011AA
C0392920
SNOMED CT 2011_0131
150415003
UMLS CUI 2011AA
C0439547
SNOMED CT 2011_0131
272105005
UMLS CUI 2011AA
C0040732
SNOMED CT 2011_0131
77465005
MedDRA 14.1
10057677
Patient eligible for standard and dose-reduced conditioning as per local guideline
Descrizione

Patient eligible for standard and dose-reduced conditioning as per local guideline

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0030705
SNOMED CT 2011_0131
116154003
UMLS CUI 2011AA
C1548635
HL7 V3 2006_05
ELG
UMLS CUI 2011AA
C2828392
UMLS CUI 2011AA
C0392756
SNOMED CT 2011_0131
260400001
UMLS CUI 2011AA
C0178602
SNOMED CT 2011_0131
260911001
UMLS CUI 2011AA
C0009647
SNOMED CT 2011_0131
78326006
UMLS CUI 2011AA
CL415116
UMLS CUI 2011AA
C0220845
Patient age 18-60 years if donor is a HLA-matched UNRELATED donor (HLA-A, HLA-B, HLA-DRB1 and HLA-DQB1) (one mismatch allowed)
Descrizione

Patient age 18-60 years if donor is a HLA-matched UNRELATED donor (HLA-A, HLA-B, HLA-DRB1 and HLA-DQB1) (one mismatch allowed)

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0001779
SNOMED CT 2011_0131
397669002
UMLS CUI 2011AA
C0750557
UMLS CUI 2011AA
CL414920
UMLS CUI 2011AA
C1315037
LOINC Version 232
MTHU000083
UMLS CUI 2011AA
C1708943
UMLS CUI 2011AA
CL414700
UMLS CUI 2011AA
CL414920
UMLS CUI 2011AA
C0019728
SNOMED CT 2011_0131
49495002
LOINC Version 232
MTHU033943
UMLS CUI 2011AA
C0019737
SNOMED CT 2011_0131
54481006
LOINC Version 232
MTHU027937
UMLS CUI 2011AA
C0122040
LOINC Version 232
MTHU019559
UMLS CUI 2011AA
C0122020
LOINC Version 232
MTHU019561
UMLS CUI 2011AA
C0205447
SNOMED CT 2011_0131
38112003
UMLS CUI 2011AA
C1881865
UMLS CUI 2011AA
C1524004
Patient age 18-65 years if donor is a HLA-matched RELATED donor (HLA-A, HLA-B, HLA-DRB1 and HLA-DQB1)(one antigen-mismatch allowed)
Descrizione

Patient age 18-65 years if donor is a HLA-matched RELATED donor (HLA-A, HLA-B, HLA-DRB1 and HLA-DQB1)(one antigen-mismatch allowed)

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0001779
SNOMED CT 2011_0131
397669002
UMLS CUI 2011AA
C0750557
UMLS CUI 2011AA
CL414920
UMLS CUI 2011AA
C1315037
LOINC Version 232
MTHU000083
UMLS CUI 2011AA
C1708943
UMLS CUI 2011AA
C0445223
SNOMED CT 2011_0131
262094002
UMLS CUI 2011AA
CL414920
UMLS CUI 2011AA
C0019728
SNOMED CT 2011_0131
49495002
LOINC Version 232
MTHU033943
UMLS CUI 2011AA
C0019737
SNOMED CT 2011_0131
54481006
LOINC Version 232
MTHU027937
UMLS CUI 2011AA
C0122040
LOINC Version 232
MTHU019559
UMLS CUI 2011AA
C0122020
LOINC Version 232
MTHU019561
UMLS CUI 2011AA
C0205447
SNOMED CT 2011_0131
38112003
UMLS CUI 2011AA
C0003320
SNOMED CT 2011_0131
7120007
LOINC Version 232
MTHU007668
UMLS CUI 2011AA
C1881865
UMLS CUI 2011AA
C1524004
no major organ dysfunction
Descrizione

no major organ dysfunction

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0332197
SNOMED CT 2011_0131
2667000
UMLS CUI 2011AA
C0205164
SNOMED CT 2011_0131
255603008
UMLS CUI 2011AA
C0178784
LOINC Version 232
MTHU020170
UMLS CUI 2011AA
C0277785
SNOMED CT 2011_0131
386585008
written informed consent of the patient
Descrizione

written informed consent of the patient

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0021430
Ausschlusskriterien
Descrizione

Ausschlusskriterien

Alias
UMLS CUI 2011AA
CL425201
Blasts >20% in bone marrow at time of transplantation
Descrizione

Blasts >20% in bone marrow at time of transplantation

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0368761
SNOMED CT 2011_0131
312256009
LOINC Version 232
MTHU005201
UMLS CUI 2011AA
C0005953
SNOMED CT 2011_0131
14016003
LOINC Version 232
MTHU016536
UMLS CUI 2011AA
C0439547
SNOMED CT 2011_0131
272105005
UMLS CUI 2011AA
C0040732
SNOMED CT 2011_0131
77465005
MedDRA 14.1
10057677
no written informed consent
Descrizione

no written informed consent

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0021430
Zentralnervensystembeteiligung, Status
Descrizione

central nervous involvement

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0007682
SNOMED CT 2011_0131
260766009
Severe irreversible renal, hepatic, pulmonary or cardiac disease, such as
Descrizione

Severe irreversible renal, hepatic, pulmonary or cardiac disease, such as

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0205082
SNOMED CT 2011_0131
24484000
UMLS CUI 2011AA
C1518422
UMLS CUI 2011AA
C0205343
SNOMED CT 2011_0131
35174006
UMLS CUI 2011AA
C0022658
SNOMED CT 2011_0131
90708001
MedDRA 14.1
10029151
ICD-10-CM Version 2010
N18.9
UMLS CUI 2011AA
C0023895
SNOMED CT 2011_0131
235856003
MedDRA 14.1
10024670
ICD-10-CM Version 2010
K76.9
ICD-9-CM Version 2011
573.9
UMLS CUI 2011AA
C0024115
SNOMED CT 2011_0131
19829001
MedDRA 14.1
10025082
ICD-10-CM Version 2010
J98.4
UMLS CUI 2011AA
C0018799
SNOMED CT 2011_0131
56265001
MedDRA 14.1
10061024
total bilirubin, SGPT or SGOT > 2 times upper the normal level
Descrizione

total bilirubin, SGPT or SGOT > 2 times upper the normal level

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0201913
SNOMED CT 2011_0131
359986008
MedDRA 14.1
10004696
UMLS CUI 2011AA
C0001899
SNOMED CT 2011_0131
56935002
LOINC Version 232
MTHU006766
UMLS CUI 2011AA
C0004002
SNOMED CT 2011_0131
26091008
LOINC Version 232
MTHU004883
UMLS CUI 2011AA
C0205172
SNOMED CT 2011_0131
242762006
UMLS CUI 2011AA
C1948050
UMLS CUI 2011AA
CL384738
UMLS CUI 2011AA
C0205307
SNOMED CT 2011_0131
17621005
HL7 V3 2006_05
N
UMLS CUI 2011AA
C0456079
SNOMED CT 2011_0131
276625007
LVEF - Left ventricular ejection fraction
Descrizione

Left ventricular ejection fraction <30%

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0428772
SNOMED CT 2011_0131
250908004
MedDRA 14.1
10069170
Kreatinin-Clearance
Descrizione

creatinine clearance <30 ml/min

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0201976
SNOMED CT 2011_0131
167181009
MedDRA 14.1
10011371
DLCO <35% and/or receiving supplementary continuous oxygen
Descrizione

DLCO <35% and/or receiving supplementary continuous oxygen

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C1516251
UMLS CUI 2011AA
C1514756
UMLS CUI 2011AA
C2348609
UMLS CUI 2011AA
C0549178
UMLS CUI 2011AA
C0030054
SNOMED CT 2011_0131
24099007
LOINC Version 232
MTHU002757
Positive serology for HIV
Descrizione

Positive serology for HIV

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0242089
SNOMED CT 2011_0131
168276008
MedDRA 14.1
10050409
UMLS CUI 2011AA
C0019682
SNOMED CT 2011_0131
19030005
pregnant or lactating women
Descrizione

pregnant or lactating women

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0549206
MedDRA 14.1
10036586
UMLS CUI 2011AA
C2828358
UMLS CUI 2011AA
C0043210
SNOMED CT 2011_0131
224526002
patients with a life-expectancy of < 6 months because of another debilitating disease
Descrizione

patients with a life-expectancy of < 6 months because of another debilitating disease

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0023671
LOINC Version 232
LP75025-4
UMLS CUI 2011AA
C0547044
SNOMED CT 2011_0131
263796003
UMLS CUI 2011AA
C2825407
UMLS CUI 2011AA
C0439234
SNOMED CT 2011_0131
258707000
HL7 V3 2006_05
Y
UMLS CUI 2011AA
CL420107
UMLS CUI 2011AA
C0205394
SNOMED CT 2011_0131
74964007
UMLS CUI 2011AA
C0004093
SNOMED CT 2011_0131
260407003
MedDRA 14.1
10011942
ICD-10-CM Version 2010
R53.1
UMLS CUI 2011AA
C0012634
SNOMED CT 2011_0131
64572001
serious psychiatric or psychological disorders
Descrizione

serious psychiatric or psychological disorders

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0205404
SNOMED CT 2011_0131
42745003
UMLS CUI 2011AA
C0004936
SNOMED CT 2011_0131
74732009
MedDRA 14.1
10037174
ICD-10-CM Version 2010
F99
ICD-9-CM Version 2011
290-319.99
invasive fungal infection at time of registration
Descrizione

invasive fungal infection at time of registration

Tipo di dati

boolean

Alias
UMLS CUI 2011AA
C0205281
SNOMED CT 2011_0131
10179008
UMLS CUI 2011AA
C0026946
SNOMED CT 2011_0131
3218000
MedDRA 14.1
10017533
ICD-10-CM Version 2010
B35-B49
ICD-9-CM Version 2011
110-118.99
UMLS CUI 2011AA
C0439547
SNOMED CT 2011_0131
272105005
UMLS CUI 2011AA
C1516879
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Similar models

Eligibility

1 moduli
  1. StudyEvent: Eligibility
    1. Eligibility
Name
genere
Description | Question | Decode (Coded Value)
Tipo di dati
Alias
Item Group
Einschlusskriterien
CL425202 (UMLS CUI 2011AA)
age 18 Years to 65 Years
Item
Alter 18 bis 65 Jahre
boolean
C0001779 (UMLS CUI 2011AA)
397669002 (SNOMED CT 2011_0131)
Disease: cytologically proven
Item
Disease: cytologically proven
boolean
C0012634 (UMLS CUI 2011AA)
64572001 (SNOMED CT 2011_0131)
C0205471 (UMLS CUI 2011AA)
40413002 (SNOMED CT 2011_0131)
C0456369 (UMLS CUI 2011AA)
277025001 (SNOMED CT 2011_0131)
primary or therapy related myelodysplastic syndrome (MDS) either as
Item
primary or therapy related myelodysplastic syndrome (MDS) either as
boolean
CL414904 (UMLS CUI 2011AA)
C3463824 (UMLS CUI 2011AA)
128623006 (SNOMED CT 2011_0131)
10028533 (MedDRA 14.1)
D46 (ICD-10-CM Version 2010)
238.75 (ICD-9-CM Version 2011)
E12552 (CTCAE 1105E)
C0011900 (UMLS CUI 2011AA)
439401001 (SNOMED CT 2011_0131)
MTHU008876 (LOINC Version 232)
C1292780 (UMLS CUI 2011AA)
128838005 (SNOMED CT 2011_0131)
refractory anaemia (RA) according FAB or RA with or without dysplasia according WHO
Item
refractory anaemia (RA) according FAB or RA with or without dysplasia according WHO
boolean
C0002893 (UMLS CUI 2011AA)
109996008 (SNOMED CT 2011_0131)
10038269 (MedDRA 14.1)
C0680240 (UMLS CUI 2011AA)
CL421536 (UMLS CUI 2011AA)
C0002893 (UMLS CUI 2011AA)
109996008 (SNOMED CT 2011_0131)
10038269 (MedDRA 14.1)
C0150312 (UMLS CUI 2011AA)
52101004 (SNOMED CT 2011_0131)
C0332197 (UMLS CUI 2011AA)
2667000 (SNOMED CT 2011_0131)
C0334044 (UMLS CUI 2011AA)
25723000 (SNOMED CT 2011_0131)
10058314 (MedDRA 14.1)
C0680240 (UMLS CUI 2011AA)
C0451584 (UMLS CUI 2011AA)
273931002 (SNOMED CT 2011_0131)
refractory anaemia with ringsideroblasts (RARS) according FAB or RARS with or without dysplasia according WHO
Item
refractory anaemia with ringsideroblasts (RARS) according FAB or RARS with or without dysplasia according WHO
boolean
C1264195 (UMLS CUI 2011AA)
109998009 (SNOMED CT 2011_0131)
10038272 (MedDRA 14.1)
D46.1 (ICD-10-CM Version 2010)
C0680240 (UMLS CUI 2011AA)
CL421536 (UMLS CUI 2011AA)
C1264195 (UMLS CUI 2011AA)
109998009 (SNOMED CT 2011_0131)
10038272 (MedDRA 14.1)
D46.1 (ICD-10-CM Version 2010)
C0150312 (UMLS CUI 2011AA)
52101004 (SNOMED CT 2011_0131)
C0332197 (UMLS CUI 2011AA)
2667000 (SNOMED CT 2011_0131)
C0334044 (UMLS CUI 2011AA)
25723000 (SNOMED CT 2011_0131)
10058314 (MedDRA 14.1)
C0680240 (UMLS CUI 2011AA)
C0451584 (UMLS CUI 2011AA)
273931002 (SNOMED CT 2011_0131)
refractory anaemia with excess of blasts (RAEB) according FAB or RAEB I or RAEB II according WHO
Item
refractory anaemia with excess of blasts (RAEB) according FAB or RAEB I or RAEB II according WHO
boolean
C0002894 (UMLS CUI 2011AA)
398623004 (SNOMED CT 2011_0131)
10038270 (MedDRA 14.1)
D46.20 (ICD-10-CM Version 2010)
C0680240 (UMLS CUI 2011AA)
CL421536 (UMLS CUI 2011AA)
C1318550 (UMLS CUI 2011AA)
415283002 (SNOMED CT 2011_0131)
D46.21 (ICD-10-CM Version 2010)
C1318551 (UMLS CUI 2011AA)
415284008 (SNOMED CT 2011_0131)
D46.22 (ICD-10-CM Version 2010)
C0680240 (UMLS CUI 2011AA)
C0451584 (UMLS CUI 2011AA)
273931002 (SNOMED CT 2011_0131)
refractory anaemia with excess of blast in transformation (RAEB-T) according FAB
Item
refractory anaemia with excess of blast in transformation (RAEB-T) according FAB
boolean
C0280028 (UMLS CUI 2011AA)
110000005 (SNOMED CT 2011_0131)
10054593 (MedDRA 14.1)
C92.0 (ICD-10-CM Version 2010)
C0680240 (UMLS CUI 2011AA)
CL421536 (UMLS CUI 2011AA)
CMML (dysplastic type) according WHO
Item
CMML (dysplastic type) according WHO
boolean
C0023480 (UMLS CUI 2011AA)
127225006 (SNOMED CT 2011_0131)
10009018 (MedDRA 14.1)
C93.1 (ICD-10-CM Version 2010)
C0334044 (UMLS CUI 2011AA)
25723000 (SNOMED CT 2011_0131)
10058314 (MedDRA 14.1)
C0680240 (UMLS CUI 2011AA)
C0451584 (UMLS CUI 2011AA)
273931002 (SNOMED CT 2011_0131)
or secondary acute myeloid leukaemia (sAML)
Item
sekundäre akute myeloische Leukämie
boolean
C0280449 (UMLS CUI 2011AA)
Blast count <20 percent in bone marrow with or without chemotherapy at time of transplantation
Item
Blast count <20 percent in bone marrow with or without chemotherapy at time of transplantation
boolean
C0523113 (UMLS CUI 2011AA)
104102000 (SNOMED CT 2011_0131)
10061700 (MedDRA 14.1)
C0005953 (UMLS CUI 2011AA)
14016003 (SNOMED CT 2011_0131)
MTHU016536 (LOINC Version 232)
C0150312 (UMLS CUI 2011AA)
52101004 (SNOMED CT 2011_0131)
C0332197 (UMLS CUI 2011AA)
2667000 (SNOMED CT 2011_0131)
C0392920 (UMLS CUI 2011AA)
150415003 (SNOMED CT 2011_0131)
C0439547 (UMLS CUI 2011AA)
272105005 (SNOMED CT 2011_0131)
C0040732 (UMLS CUI 2011AA)
77465005 (SNOMED CT 2011_0131)
10057677 (MedDRA 14.1)
Patient eligible for standard and dose-reduced conditioning as per local guideline
Item
Patient eligible for standard and dose-reduced conditioning as per local guideline
boolean
C0030705 (UMLS CUI 2011AA)
116154003 (SNOMED CT 2011_0131)
C1548635 (UMLS CUI 2011AA)
ELG (HL7 V3 2006_05)
C2828392 (UMLS CUI 2011AA)
C0392756 (UMLS CUI 2011AA)
260400001 (SNOMED CT 2011_0131)
C0178602 (UMLS CUI 2011AA)
260911001 (SNOMED CT 2011_0131)
C0009647 (UMLS CUI 2011AA)
78326006 (SNOMED CT 2011_0131)
CL415116 (UMLS CUI 2011AA)
C0220845 (UMLS CUI 2011AA)
Patient age 18-60 years if donor is a HLA-matched UNRELATED donor (HLA-A, HLA-B, HLA-DRB1 and HLA-DQB1) (one mismatch allowed)
Item
Patient age 18-60 years if donor is a HLA-matched UNRELATED donor (HLA-A, HLA-B, HLA-DRB1 and HLA-DQB1) (one mismatch allowed)
boolean
C0001779 (UMLS CUI 2011AA)
397669002 (SNOMED CT 2011_0131)
C0750557 (UMLS CUI 2011AA)
CL414920 (UMLS CUI 2011AA)
C1315037 (UMLS CUI 2011AA)
MTHU000083 (LOINC Version 232)
C1708943 (UMLS CUI 2011AA)
CL414700 (UMLS CUI 2011AA)
CL414920 (UMLS CUI 2011AA)
C0019728 (UMLS CUI 2011AA)
49495002 (SNOMED CT 2011_0131)
MTHU033943 (LOINC Version 232)
C0019737 (UMLS CUI 2011AA)
54481006 (SNOMED CT 2011_0131)
MTHU027937 (LOINC Version 232)
C0122040 (UMLS CUI 2011AA)
MTHU019559 (LOINC Version 232)
C0122020 (UMLS CUI 2011AA)
MTHU019561 (LOINC Version 232)
C0205447 (UMLS CUI 2011AA)
38112003 (SNOMED CT 2011_0131)
C1881865 (UMLS CUI 2011AA)
C1524004 (UMLS CUI 2011AA)
Patient age 18-65 years if donor is a HLA-matched RELATED donor (HLA-A, HLA-B, HLA-DRB1 and HLA-DQB1)(one antigen-mismatch allowed)
Item
Patient age 18-65 years if donor is a HLA-matched RELATED donor (HLA-A, HLA-B, HLA-DRB1 and HLA-DQB1)(one antigen-mismatch allowed)
boolean
C0001779 (UMLS CUI 2011AA)
397669002 (SNOMED CT 2011_0131)
C0750557 (UMLS CUI 2011AA)
CL414920 (UMLS CUI 2011AA)
C1315037 (UMLS CUI 2011AA)
MTHU000083 (LOINC Version 232)
C1708943 (UMLS CUI 2011AA)
C0445223 (UMLS CUI 2011AA)
262094002 (SNOMED CT 2011_0131)
CL414920 (UMLS CUI 2011AA)
C0019728 (UMLS CUI 2011AA)
49495002 (SNOMED CT 2011_0131)
MTHU033943 (LOINC Version 232)
C0019737 (UMLS CUI 2011AA)
54481006 (SNOMED CT 2011_0131)
MTHU027937 (LOINC Version 232)
C0122040 (UMLS CUI 2011AA)
MTHU019559 (LOINC Version 232)
C0122020 (UMLS CUI 2011AA)
MTHU019561 (LOINC Version 232)
C0205447 (UMLS CUI 2011AA)
38112003 (SNOMED CT 2011_0131)
C0003320 (UMLS CUI 2011AA)
7120007 (SNOMED CT 2011_0131)
MTHU007668 (LOINC Version 232)
C1881865 (UMLS CUI 2011AA)
C1524004 (UMLS CUI 2011AA)
no major organ dysfunction
Item
no major organ dysfunction
boolean
C0332197 (UMLS CUI 2011AA)
2667000 (SNOMED CT 2011_0131)
C0205164 (UMLS CUI 2011AA)
255603008 (SNOMED CT 2011_0131)
C0178784 (UMLS CUI 2011AA)
MTHU020170 (LOINC Version 232)
C0277785 (UMLS CUI 2011AA)
386585008 (SNOMED CT 2011_0131)
written informed consent of the patient
Item
written informed consent of the patient
boolean
C0021430 (UMLS CUI 2011AA)
Item Group
Ausschlusskriterien
CL425201 (UMLS CUI 2011AA)
Blasts >20% in bone marrow at time of transplantation
Item
Blasts >20% in bone marrow at time of transplantation
boolean
C0368761 (UMLS CUI 2011AA)
312256009 (SNOMED CT 2011_0131)
MTHU005201 (LOINC Version 232)
C0005953 (UMLS CUI 2011AA)
14016003 (SNOMED CT 2011_0131)
MTHU016536 (LOINC Version 232)
C0439547 (UMLS CUI 2011AA)
272105005 (SNOMED CT 2011_0131)
C0040732 (UMLS CUI 2011AA)
77465005 (SNOMED CT 2011_0131)
10057677 (MedDRA 14.1)
no written informed consent
Item
no written informed consent
boolean
C0021430 (UMLS CUI 2011AA)
central nervous involvement
Item
Zentralnervensystembeteiligung, Status
boolean
C0007682 (UMLS CUI 2011AA)
260766009 (SNOMED CT 2011_0131)
Severe irreversible renal, hepatic, pulmonary or cardiac disease, such as
Item
Severe irreversible renal, hepatic, pulmonary or cardiac disease, such as
boolean
C0205082 (UMLS CUI 2011AA)
24484000 (SNOMED CT 2011_0131)
C1518422 (UMLS CUI 2011AA)
C0205343 (UMLS CUI 2011AA)
35174006 (SNOMED CT 2011_0131)
C0022658 (UMLS CUI 2011AA)
90708001 (SNOMED CT 2011_0131)
10029151 (MedDRA 14.1)
N18.9 (ICD-10-CM Version 2010)
C0023895 (UMLS CUI 2011AA)
235856003 (SNOMED CT 2011_0131)
10024670 (MedDRA 14.1)
K76.9 (ICD-10-CM Version 2010)
573.9 (ICD-9-CM Version 2011)
C0024115 (UMLS CUI 2011AA)
19829001 (SNOMED CT 2011_0131)
10025082 (MedDRA 14.1)
J98.4 (ICD-10-CM Version 2010)
C0018799 (UMLS CUI 2011AA)
56265001 (SNOMED CT 2011_0131)
10061024 (MedDRA 14.1)
total bilirubin, SGPT or SGOT > 2 times upper the normal level
Item
total bilirubin, SGPT or SGOT > 2 times upper the normal level
boolean
C0201913 (UMLS CUI 2011AA)
359986008 (SNOMED CT 2011_0131)
10004696 (MedDRA 14.1)
C0001899 (UMLS CUI 2011AA)
56935002 (SNOMED CT 2011_0131)
MTHU006766 (LOINC Version 232)
C0004002 (UMLS CUI 2011AA)
26091008 (SNOMED CT 2011_0131)
MTHU004883 (LOINC Version 232)
C0205172 (UMLS CUI 2011AA)
242762006 (SNOMED CT 2011_0131)
C1948050 (UMLS CUI 2011AA)
CL384738 (UMLS CUI 2011AA)
C0205307 (UMLS CUI 2011AA)
17621005 (SNOMED CT 2011_0131)
N (HL7 V3 2006_05)
C0456079 (UMLS CUI 2011AA)
276625007 (SNOMED CT 2011_0131)
Left ventricular ejection fraction <30%
Item
LVEF - Left ventricular ejection fraction
boolean
C0428772 (UMLS CUI 2011AA)
250908004 (SNOMED CT 2011_0131)
10069170 (MedDRA 14.1)
creatinine clearance <30 ml/min
Item
Kreatinin-Clearance
boolean
C0201976 (UMLS CUI 2011AA)
167181009 (SNOMED CT 2011_0131)
10011371 (MedDRA 14.1)
DLCO <35% and/or receiving supplementary continuous oxygen
Item
DLCO <35% and/or receiving supplementary continuous oxygen
boolean
C1516251 (UMLS CUI 2011AA)
C1514756 (UMLS CUI 2011AA)
C2348609 (UMLS CUI 2011AA)
C0549178 (UMLS CUI 2011AA)
C0030054 (UMLS CUI 2011AA)
24099007 (SNOMED CT 2011_0131)
MTHU002757 (LOINC Version 232)
Positive serology for HIV
Item
Positive serology for HIV
boolean
C0242089 (UMLS CUI 2011AA)
168276008 (SNOMED CT 2011_0131)
10050409 (MedDRA 14.1)
C0019682 (UMLS CUI 2011AA)
19030005 (SNOMED CT 2011_0131)
pregnant or lactating women
Item
pregnant or lactating women
boolean
C0549206 (UMLS CUI 2011AA)
10036586 (MedDRA 14.1)
C2828358 (UMLS CUI 2011AA)
C0043210 (UMLS CUI 2011AA)
224526002 (SNOMED CT 2011_0131)
patients with a life-expectancy of < 6 months because of another debilitating disease
Item
patients with a life-expectancy of < 6 months because of another debilitating disease
boolean
C0023671 (UMLS CUI 2011AA)
LP75025-4 (LOINC Version 232)
C0547044 (UMLS CUI 2011AA)
263796003 (SNOMED CT 2011_0131)
C2825407 (UMLS CUI 2011AA)
C0439234 (UMLS CUI 2011AA)
258707000 (SNOMED CT 2011_0131)
Y (HL7 V3 2006_05)
CL420107 (UMLS CUI 2011AA)
C0205394 (UMLS CUI 2011AA)
74964007 (SNOMED CT 2011_0131)
C0004093 (UMLS CUI 2011AA)
260407003 (SNOMED CT 2011_0131)
10011942 (MedDRA 14.1)
R53.1 (ICD-10-CM Version 2010)
C0012634 (UMLS CUI 2011AA)
64572001 (SNOMED CT 2011_0131)
serious psychiatric or psychological disorders
Item
serious psychiatric or psychological disorders
boolean
C0205404 (UMLS CUI 2011AA)
42745003 (SNOMED CT 2011_0131)
C0004936 (UMLS CUI 2011AA)
74732009 (SNOMED CT 2011_0131)
10037174 (MedDRA 14.1)
F99 (ICD-10-CM Version 2010)
290-319.99 (ICD-9-CM Version 2011)
invasive fungal infection at time of registration
Item
invasive fungal infection at time of registration
boolean
C0205281 (UMLS CUI 2011AA)
10179008 (SNOMED CT 2011_0131)
C0026946 (UMLS CUI 2011AA)
3218000 (SNOMED CT 2011_0131)
10017533 (MedDRA 14.1)
B35-B49 (ICD-10-CM Version 2010)
110-118.99 (ICD-9-CM Version 2011)
C0439547 (UMLS CUI 2011AA)
272105005 (SNOMED CT 2011_0131)
C1516879 (UMLS CUI 2011AA)
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