Description:

Combination Chemotherapy Followed By Radiation Therapy in Treating Patients With Aggressive Non-Hodgkin's Lymphoma DISEASE CHARACTERISTICS: - Histologically confirmed aggressive non-Hodgkin's lymphoma - Previously untreated disease - Favorable prognosis - International Prognostic Index score of 0-1 - No more than 25% marrow involvement PATIENT CHARACTERISTICS: Age - 18 to 60 Performance status - ECOG 0-3 OR - Karnofsky 40-100% Life expectancy - Not specified Hematopoietic - Platelet count at least 100,000/mm^3 - WBC at least 2,500/mm^3 Hepatic - No active hepatitis infection Renal - Not specified Other - HIV negative - Not pregnant or nursing - No relevant accompanying disease - No other concurrent malignancy - No contraindications to any study medications - No prior noncompliance by patient PRIOR CONCURRENT THERAPY: Biologic therapy - Not specified Chemotherapy - No prior chemotherapy Endocrine therapy - Not specified Radiotherapy - No prior radiotherapy Surgery - Not specified Other - No other concurrent participation in another treatment study

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Versions (2)
  1. 12/9/13 12/9/13 - Martin Dugas
  2. 9/17/21 9/17/21 -
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December 9, 2013

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Creative Commons BY-NC 3.0 Legacy
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Eligibility NCT00053768 NHL

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Details

Eligibility

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  1. StudyEvent: Eligibility
    1. Eligibility
Disease characteristics
Histologically confirmed aggressive non-Hodgkin's lymphoma
Previously untreated disease
Favorable prognosis
International Prognostic Index score of 0-1
No more than 25% marrow involvement
Patient characteristics and prior concurrent therapy
Age 18 to 60
ECOG 0-3 OR Karnofsky 40-100%
Platelet count at least 100,000/mm^3
WBC at least 2,500/mm^3
No active hepatitis infection
HIV negative; Not pregnant or nursing; No relevant accompanying disease; No other concurrent malignancy; No contraindications to any study medications; No prior noncompliance by patient
No prior chemotherapy
No prior radiotherapy
No other concurrent participation in another treatment study
Medical Concepts
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