Eligibility NCT00053768 NHL

Combination Chemotherapy Followed By Radiation Therapy in Treating Patients With Aggressive Non-Hodgkin's Lymphoma DISEASE CHARACTERISTICS: - Histologically confirmed aggressive non-Hodgkin's lymphoma - Previously untreated disease - Favorable prognosis - International Prognostic Index score of 0-1 - No more than 25% marrow involvement PATIENT CHARACTERISTICS: Age - 18 to 60 Performance status - ECOG 0-3 OR - Karnofsky 40-100% Life expectancy - Not specified Hematopoietic - Platelet count at least 100,000/mm^3 - WBC at least 2,500/mm^3 Hepatic - No active hepatitis infection Renal - Not specified Other - HIV negative - Not pregnant or nursing - No relevant accompanying disease - No other concurrent malignancy - No contraindications to any study medications - No prior noncompliance by patient PRIOR CONCURRENT THERAPY: Biologic therapy - Not specified Chemotherapy - No prior chemotherapy Endocrine therapy - Not specified Radiotherapy - No prior radiotherapy Surgery - Not specified Other - No other concurrent participation in another treatment study

Eligibility

  1. StudyEvent: Eligibility
    1. Eligibility
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Disease characteristics
NHL
Item
Histologically confirmed aggressive non-Hodgkin's lymphoma
boolean
Previously untreated disease
Item
Previously untreated disease
boolean
Prognosis
Item
Favorable prognosis
boolean
International Prognostic Index score
Item
International Prognostic Index score of 0-1
boolean
Bone marrow involvement
Item
No more than 25% marrow involvement
boolean
Item Group
Patient characteristics and prior concurrent therapy
Age
Item
Age 18 to 60
boolean
Performance status
Item
ECOG 0-3 OR Karnofsky 40-100%
boolean
Platelet count
Item
Platelet count at least 100,000/mm^3
boolean
WBC
Item
WBC at least 2,500/mm^3
boolean
Hepatitis
Item
No active hepatitis infection
boolean
Other
Item
HIV negative; Not pregnant or nursing; No relevant accompanying disease; No other concurrent malignancy; No contraindications to any study medications; No prior noncompliance by patient
boolean
Chemotherapy
Item
No prior chemotherapy
boolean
Radiotherapy
Item
No prior radiotherapy
boolean
Enrollment
Item
No other concurrent participation in another treatment study
boolean
Item Group
Medical Concepts
Diagnosis
Item
Diagnosis
string
C0011900 (UMLS CUI)
439401001 (SNOMED CT 2010_0731)
Therapeutic procedure
Item
Therapeutic procedure
string
C0087111 (UMLS CUI)
Pharmaceutical Preparations
Item
Medication
string
C0013227 (UMLS CUI)
International Prognostic Index
Item
International Prognostic Index
string
C1512894 (UMLS CUI)
Bone Marrow Involvement
Item
Bone Marrow Involvement
string
C1517677 (UMLS CUI)
Age
Item
Age
string
C0001779 (UMLS CUI)
102518004 (SNOMED CT 2010_0731)
ECOG performance status
Item
ECOG performance status
string
423740007 (SNOMED CT 2010_0731)
Karnofsky performance status
Item
Karnofsky performance status
string
273546003 (SNOMED CT 2010_0731)
Platelet count - finding (Code )
Item
Platelet count - finding
string
365632008 (SNOMED CT 2010_0731)
C1287267 (UMLS CUI)
777-3 (LOINC)
WBC
Item
White blood cell count
string
767002 (SNOMED CT 2010_0731)
6690-2 (LOINC)
Hepatitis
Item
Hepatitis
string
29001004 (SNOMED CT 2010_0731)
C0019158 (UMLS CUI)
10019717 (MedDRA 13.1)
HIV negative
Item
HIV negative
string
C0481430 (UMLS CUI)
143223008 (SNOMED CT 2010_0731)
pregnant
Item
pregnant
string
C0549206 (UMLS CUI)
10036586 (MedDRA 13.1)
Breast feeding
Item
Breast feeding
string
C0006147 (UMLS CUI)
10006247 (MedDRA 13.1)
Contraindication to medical treatment
Item
Contraindication to medical treatment
string
C1301624 (UMLS CUI)
10010833 (MedDRA 13.1)
Treatment noncompliance
Item
Treatment noncompliance
string
C0376405 (UMLS CUI)
10049414 (MedDRA 13.1)
Chemotherapy
Item
Cancer chemotherapy
string
C0392920 (UMLS CUI)
150415003 (SNOMED CT 2010_0731)
Radiotherapy
Item
Radiotherapy
string
C1522449 (UMLS CUI)
302505005 (SNOMED CT 2010_0731)
Enrollment
Item
Enrollment
string
C1516879 (UMLS CUI)

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